[1,3]Thiazolo[5,4-H]quinoline

Base Information

Chemical Name:[1,3]Thiazolo[5,4-H]quinoline
CAS No.:233-94-3
Molecular Formula:C₁₀H₆N₂S
Molecular Weight:186.237
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10603243
Wikidata:Q82500573
Mol file:233-94-3.mol

Synonyms:233-94-3;[1,3]THIAZOLO[5,4-H]QUINOLINE;SCHEMBL10690151;DTXSID10603243

Suppliers and Price of [1,3]Thiazolo[5,4-H]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of [1,3]Thiazolo[5,4-H]quinoline

Chemical Property:

Melting Point:158 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling Point:363.0±15.0 °C(Predicted)
PKA:0.81±0.40(Predicted)
PSA：54.02000
Density:1.394±0.06 g/cm3(Predicted)
LogP:2.84450
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:186.02516937
Heavy Atom Count:13
Complexity:197

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C3=C(C=C2)SC=N3)N=C1

Technology Process of [1,3]Thiazolo[5,4-H]quinoline

There total 5 articles about [1,3]Thiazolo[5,4-H]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6973-51-9
2-amino-4-nitrobenzothiazole

: 233-94-3
thiazolo[5,4-h]quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: NaNO₂; aqueous HNO₃; H₃PO₄ / anschliessend Einwirkung von Kupfer in wss. HCl

2: red phosphorus; aqueous HI; acetic acid

3: as2O₅; concentrated H₂SO₄

With phosphorus; arsenic(V) oxide; phosphoric acid; sulfuric acid; hydrogen iodide; nitric acid; acetic acid; sodium nitrite;
DOI:10.1002/hlca.19400230141

Reference yield:

: 51039-84-0
N-(2-nitrophenyl)thiourea

: 233-94-3
thiazolo[5,4-h]quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: bromine; CHCl₃ / Behandeln des Reaktionsprodukts mit wss. Bisulfit

2: NaNO₂; aqueous HNO₃; H₃PO₄ / anschliessend Einwirkung von Kupfer in wss. HCl

3: red phosphorus; aqueous HI; acetic acid

4: as2O₅; concentrated H₂SO₄

With phosphorus; arsenic(V) oxide; chloroform; phosphoric acid; sulfuric acid; hydrogen iodide; bromine; nitric acid; acetic acid; sodium nitrite;
DOI:10.1002/hlca.19400230141

Reference yield:

: 855283-00-0
2-chloro-benzothiazol-4-ylamine

: 233-94-3
thiazolo[5,4-h]quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: red phosphorus; aqueous HI; acetic acid

2: as2O₅; concentrated H₂SO₄

With phosphorus; arsenic(V) oxide; sulfuric acid; hydrogen iodide; acetic acid;
DOI:10.1002/hlca.19400230141