CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER

Base Information

• Chemical Name: CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER
• CAS No.: 196200-04-1
• Molecular Formula: C9H20 N2 O2
• Molecular Weight: 188.27
• Hs Code.: 2924297099
• Mol file: 196200-04-1.mol

Synonyms:N-tert-Butoxycarbonyl-N',N'-dimethylethylenediamine

Chemical Property of CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER

Chemical Property:

• Boiling Point: 256.8±23.0 °C(Predicted)
• PKA: 12.67±0.46(Predicted)
• PSA: 41.57000
• Density: 0.957±0.06 g/cm3(Predicted)
• LogP: 1.46360
• Storage Temp.: -20?C Freezer

Purity/Quality:

98%Min ^*data from raw suppliers

N,N-Dimethyl-N’-(t-butoxycarbonyl)ethyleneDiamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: N,N-Dimethyl-N’-(t-butoxycarbonyl)ethylene Diamine (cas# 196200-04-1) is a compound useful in organic synthesis.

Technology Process of CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER

There total 3 articles about CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

di-tert-butyl dicarbonate (24424-99-5) + N,N-dimethylethylenediamine (108-00-9) → tert-butyl (2-(dimethylamino)ethyl)carbamate (196200-04-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

Reference yield: 93.0%

tert-butyldicarbonate (34619-03-9) + N,N-dimethylethylenediamine (108-00-9) → tert-butyl (2-(dimethylamino)ethyl)carbamate (196200-04-1)

Guidance literature:

In dichloromethane; at 4 ℃;

DOI:10.1039/c2tb00404f

Reference yield:

(S)-benzyl 2-(3-chloropropylamino)propanoate + di-tert-butyl dicarbonate (24424-99-5) + N,N-dimethylethylenediamine (108-00-9) → (S)-benzyl 2-((tert-butoxycarbonyl)(3-chloropropyl)amino)propanoate + tert-butyl (2-(dimethylamino)ethyl)carbamate (196200-04-1) + (S)-benzyl 2-(azetidin-1-yl)propanoate + C16H23Cl2NO2

Guidance literature:

(S)-benzyl 2-(3-chloropropylamino)propanoate; di-tert-butyl dicarbonate; In tert-butyl methyl ether; at 25 ℃;

N,N-dimethylethylenediamine; In tert-butyl methyl ether; at 25 ℃; for 1h;

DOI:10.1021/acs.joc.8b02866

upstream raw materials:

tert-butyldicarbonate

N,N-dimethylethylenediamine

di-tert-butyl dicarbonate

Downstream raw materials:

2-((tert-butoxycarbonyl)amino)-N,N,N-trimethylethan-1-aminium