Technology Process of 2-Pyridinemethanol,4-ethenyl-(9CI)
There total 2 articles about 2-Pyridinemethanol,4-ethenyl-(9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0);
In
toluene;
for 2h;
Inert atmosphere;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ethanol; sodium tetrahydroborate / 18 h / 20 °C / Inert atmosphere
2: bis-triphenylphosphine-palladium(II) chloride / toluene / 36 h / 50 - 80 °C / Inert atmosphere
With
sodium tetrahydroborate; ethanol;
bis-triphenylphosphine-palladium(II) chloride;
In
toluene;
-
-
1381809-27-3
(E)-(1S,14R,15R,18S,21S)-21-(3-hydroxy-benzyl)-18-isopropyl-14-methoxy-15-methyl-3-oxa-6,17,20,23,27-pentaaza-tricyclo[21.3.1.1*5,9*]octacosa-5,7,9(28),10-tetraene-2,16,19,22-tetraone
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C
2.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / 0 °C / Inert atmosphere
2.2: 0 °C / Inert atmosphere
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / acetonitrile / 4 h / 20 °C
4.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / 1,2-dichloro-ethane / 3 h / 80 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere
With
dmap; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; acetonitrile;