3-cyclohexylprop-2-enyl bromide

Base Information

• Chemical Name: 3-cyclohexylprop-2-enyl bromide
• CAS No.: 131665-81-1
• Molecular Formula: C₉H₁₅Br
• Molecular Weight: 203.122
• Mol file: 131665-81-1.mol

Synonyms:3-cyclohexylprop-2-enyl bromide

Chemical Property of 3-cyclohexylprop-2-enyl bromide

Chemical Property:

Purity/Quality:

(3-bromoprop-1-en-1-yl)cyclohexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-cyclohexylprop-2-enyl bromide

There total 6 articles about 3-cyclohexylprop-2-enyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-cyclohexyl-2-propen-1-ol (42134-55-4,114096-03-6,132350-24-4) → 3-cyclohexylprop-2-enyl bromide (131665-81-1)

Guidance literature:

With phosphorus tribromide; for 4h; Ambient temperature;

Reference yield:

vinylcyclohexane (695-12-5,25498-06-0) + allyl bromide (106-95-6) → 3-cyclohexylprop-2-enyl bromide (131665-81-1)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1039/d0cc01316a

Reference yield:

cyclohexanecarbaldehyde (2043-61-0) → 3-cyclohexylprop-2-enyl bromide (131665-81-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / toluene / 0 °C

1.2: 20 °C

2.1: diisobutylaluminium hydride / dichloromethane / -78 °C

3.1: phosphorus tribromide / diethyl ether / 0 °C

With phosphorus tribromide; sodium hydride; diisobutylaluminium hydride; In diethyl ether; dichloromethane; toluene; 1.1: |Horner-Wadsworth-Emmons Olefination / 1.2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1002/ejoc.201301360

upstream raw materials:

3-cyclohexyl-2-propen-1-ol

1-cyclohexylprop-2-en-1-ol

cyclohexanecarbaldehyde

3-cyclohexylacrylic acid ethyl ester

Downstream raw materials:

(E)-(3-cyclohexylallyl)dimethyl(phenyl)silane

pent-1-en-1-ylcyclohexane

(+)-(R)-3-cyclohexyl-3-(3,4-dichlorophenyl)prop-1-ene

(+)-(R)-3-cyclohexyl-3-(3,4-methylenedioxyphenyl)prop-1-ene