cyclohexane, 1-penten-1-yl-

Base Information

• Chemical Name: cyclohexane, 1-penten-1-yl-
• CAS No.: 5729-53-3
• Molecular Formula: C₁₁H₂₀
• Molecular Weight: 152.28
• Mol file: 5729-53-3.mol

Synonyms:pent-1-en-1-ylcyclohexane

Chemical Property of cyclohexane, 1-penten-1-yl-

Chemical Property:

• Vapor Pressure: 0.503mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexane, 1-penten-1-yl-

There total 8 articles about cyclohexane, 1-penten-1-yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

cyclohexanecarbaldehyde (2043-61-0) + pentyl 3,5-bis(trifluoromethyl)phenyl sulfone (667458-80-2) → pent-1-en-1-ylcyclohexane (5729-53-3)

Guidance literature:

pentyl 3,5-bis(trifluoromethyl)phenyl sulfone; With phosphazene base; In tetrahydrofuran; for 0.5h;

cyclohexanecarbaldehyde; In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1021/jo050852n

Reference yield: 64.0%

C22H30BLi + cyclohexanecarbaldehyde (2043-61-0) → pent-1-en-1-ylcyclohexane (5729-53-3)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; -127 deg C_. 1 h, then room t., 16 h;

DOI:10.1016/S0040-4020(01)87983-7

Reference yield:

ethylmagnesium bromide (925-90-6) + 3-cyclohexylprop-2-enyl bromide (131665-81-1) → pent-1-en-1-ylcyclohexane (5729-53-3) + (S)-(pent-1-en-3-yl)cyclohexane + (S)-(pent-1-en-3-yl)cyclohexane

Guidance literature:

With C₃₁H₃₁N₂O⁽¹⁺⁾*Cl^(1-); In diethyl ether; at -15 ℃; for 3h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.201000577

upstream raw materials:

butylidenetriphenylphosphorane

cyclohexanecarbaldehyde

pentyl 3,5-bis(trifluoromethyl)phenyl sulfone

ethylmagnesium bromide

Refernces

• 1、 Grassi, David,Dolka, Chrysanthi,Jackowski, Olivier,Alexakis, Alexandre. "Copper-free asymmetric allylic alkylation with a grignard reagent: Design of the ligand and mechanistic studies". supporting information. p. 1466 - 1475. Retrieved 2013/02/25.
• 2、 Alonso, Diego A.,Fuensanta, Monica,Najera, Carmen,Varea, Montserrat. "3,5-Bis(trifluoromethyl)phenyl sulfones in the direct Julia-Kocienski olefination". . p. 6404 - 6416. Retrieved 2007/10/03.