N-benzoyl-N-phenylaminoacetonitrile

Base Information

• Chemical Name: N-benzoyl-N-phenylaminoacetonitrile
• CAS No.: 14101-08-7
• Molecular Formula: C₁₅H₁₂N₂O
• Molecular Weight: 236.273
• Mol file: 14101-08-7.mol

Synonyms:N-benzoyl-N-phenylaminoacetonitrile

Chemical Property of N-benzoyl-N-phenylaminoacetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzoyl-N-phenylaminoacetonitrile

There total 2 articles about N-benzoyl-N-phenylaminoacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-phenylglycinonitrile (3009-97-0) + benzoyl chloride (98-88-4) → N-benzoyl-N-phenylaminoacetonitrile (14101-08-7)

Guidance literature:

With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

DOI:10.1039/c7cc05315k

Reference yield:

→ N-benzoyl-N-phenylaminoacetonitrile (14101-08-7)

Guidance literature:

Anilino-acetonitril, Benzoylchlorid / Pyridin-Ae.;

Reference yield: 93.0%

N-benzoyl-N-phenylaminoacetonitrile (14101-08-7) → N-(2-amino-2-oxoethyl)-N-phenylbenzamide

Guidance literature:

With formic acid; at 20 ℃; for 3h;

upstream raw materials:

N-phenylglycinonitrile

benzoyl chloride

Downstream raw materials:

5-amino-2,3-diphenyl-4-trifluoroacetyl-oxazolium betaine

4-(3,4-dimethoxyphenyl)-1,2-diphenyl-1H-imidazole

Refernces

• 1、 Yu, Haihua,Xiao, Li,Yang, Xicheng,Shao, Liming. "Controllable access to multi-substituted imidazoles: Via palladium(II)-catalyzed C-C coupling and C-N condensation cascade reactions". supporting information. p. 9745 - 9748. Retrieved 2017/09/07.