2-[ethoxy(hydroxy)methylidene]-1H-indene-1,3(2H)-dione

Base Information

• Chemical Name: 2-[ethoxy(hydroxy)methylidene]-1H-indene-1,3(2H)-dione
• CAS No.: 91446-49-0
• Molecular Formula: C12H9 O4 . Na
• Molecular Weight: 240.191
• Mol file: 91446-49-0.mol

Synonyms:1H-Indene-2-carboxylicacid, 2,3-dihydro-1,3-dioxo-, ethyl ester, ion(1-), sodium (9CI);2-Indancarboxylic acid, 1,3-dioxo-, ethyl ester, sodium deriv. (6CI); Ethyl1,3-indandione-2-carboxylate sodium salt; Sodium ethyl1,3-indandione-2-carboxylate

Chemical Property of 2-[ethoxy(hydroxy)methylidene]-1H-indene-1,3(2H)-dione

Chemical Property:

• Vapor Pressure: 1.6E-05mmHg at 25°C
• Boiling Point: 350.8°Cat760mmHg
• Flash Point: 136.7°C
• Density: 1.387g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[ethoxy(hydroxy)methylidene]-1H-indene-1,3(2H)-dione

There total 2 articles about 2-[ethoxy(hydroxy)methylidene]-1H-indene-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

Diethyl phthalate (84-66-2) → sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate (91446-49-0)

Guidance literature:

With sodium; In para-xylene; ethyl acetate; at 140 ℃; for 4.5h;

DOI:10.1016/j.tetlet.2014.03.014

Reference yield:

→ sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate (91446-49-0)

Guidance literature:

With sodium ethanolate; anschliessendes Erwaermen mit Essigester;

Reference yield: 73.0%

4-nitrobenzaldehdye (555-16-8) + sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate (91446-49-0) → 2-(p-nitrobenzylidene)indan-1,3-dione (15875-60-2)

Guidance literature:

sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate; With sulfuric acid; acetic acid; at 50 ℃; for 0.0833333h;

4-nitrobenzaldehdye; at 50 ℃; for 1h;

DOI:10.1016/j.tetlet.2014.03.014

upstream raw materials:

Diethyl phthalate

Downstream raw materials:

2,2-diphenyl-1,3-indanedione

1,3-Dioxo-2-phenyl-indan-carbonsaeure-⁽²⁾-aethylester

1,3-Dioxo-2-phenyl-indan-carbonsaeure-⁽²⁾-t-butylester

2-(p-nitrobenzylidene)indan-1,3-dione