3-[1-[Di(methyl-d3)amino]ethyl]phenol

Base Information

Chemical Name:3-[1-[Di(methyl-d3)amino]ethyl]phenol
CAS No.:194930-03-5
Molecular Formula:C₁₀H₁₅NO
Molecular Weight:171.188
Hs Code.:
DSSTox Substance ID:DTXSID90442016
Mol file:194930-03-5.mol

Synonyms:3-[1-[Di(methyl-d3)amino]ethyl]phenol;194930-03-5;3-[1-[bis(trideuteriomethyl)amino]ethyl]phenol;Desethyl(methyl)carbamic acid rivastigmine-d6;DTXSID90442016;HY-W101470S;AKOS030241705;CS-0203284;J-012624

Suppliers and Price of 3-[1-[Di(methyl-d3)amino]ethyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
NAP 226-90-d6
1mg
$ 425.00

TRC
3-[1-[Di(methyl-d3)amino]ethyl]phenol
1mg
$ 110.00

Medical Isotopes, Inc.
NAP226-90-d6
5 mg
$ 2000.00

Total 2 raw suppliers

Chemical Property of 3-[1-[Di(methyl-d3)amino]ethyl]phenol

Chemical Property:

Vapor Pressure:0.023mmHg at 25°C
Melting Point:111-114°C
Refractive Index:1.539
Boiling Point:241.337°C at 760 mmHg
Flash Point:97.243°C
PSA：23.47000
Density:1.059g/cm³
LogP:2.01480
Storage Temp.:Refrigerator
Solubility.:Chloroform, Dichloromethane, Methanol
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:171.153024578
Heavy Atom Count:12
Complexity:136

Purity/Quality:

99% ^*data from raw suppliers

NAP 226-90-d6 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC(=CC=C1)O)N(C)C
Isomeric SMILES:[2H]C([2H])([2H])N(C(C)C1=CC(=CC=C1)O)C([2H])([2H])[2H]
Uses A labelled metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor An active (major) metabolite of Rivastigmine.

Technology Process of 3-[1-[Di(methyl-d3)amino]ethyl]phenol

There total 1 articles about 3-[1-[Di(methyl-d3)amino]ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14802-36-9
dimethylamine-D₆

: 121-71-1
3-Hydroxyacetophenone

: 194930-03-5
(R,S)-3-[(1-di(2H3)methylamino)ethyl]phenol

Guidance literature:: With sodium cyanoborohydride; Yield given. Multistep reaction; 1.) MeOH, RT, 15 min, 2.) MeOH, RT, 30 min;
DOI:10.1002/(SICI)1099-1344(199708)39:8<651::AID-JLCR14>3.0.CO;2-8

Reference yield:

: 42252-34-6
N-ethyl-N-methylcarbamoyl chloride

: 194930-03-5
(R,S)-3-[(1-di(2H3)methylamino)ethyl]phenol

: (R,S)-N-ethyl-N-methyl-3-[(1-di(2H₃)methylamino)ethyl]carbamic acid, phenyl ester

Guidance literature:: With sodium hydride; Multistep reaction; 1.) THF, 0 deg C, 2.) THF, 0 deg C, 3 h;
DOI:10.1002/(SICI)1099-1344(199708)39:8<651::AID-JLCR14>3.0.CO;2-8