Technology Process of N-succinimide
There total 5 articles about N-succinimide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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6102-41-6,6102-44-9,14116-78-0,70749-10-9,70749-11-0,78341-47-6
rel-(4aS,8aS)-1,2,3,4,4a,5,8,8a-octahydronaphthalen-2-one
- Guidance literature:
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Multi-step reaction with 4 steps
1: 83 percent / lithium aluminum hydride / tetrahydrofuran / 1.) -70 deg C, 75 min, 2.) 3 h
2: 62 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1.) 0 deg C, 45 min, 2.) room temperature, 30 min
3: 1.) ozone, 2.) sodium borohydride / methanol / 1.) -78 deg C, 43 min
4: 1.) o-nitrophenyl selenocyanate, tri-n-butylphosphine, 2.) aq. hydrogen peroxide / 1.) THF, 0 deg C, 15 min; room temperature, 45 min, 2.) 0 deg C, 20 min; 30 min
With
sodium tetrahydroborate; lithium aluminium tetrahydride; ortho-nitrophenyl selenocyanate; tributylphosphine; dihydrogen peroxide; ozone; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja00343a030
- Guidance literature:
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Multi-step reaction with 2 steps
1: 1.) ozone, 2.) sodium borohydride / methanol / 1.) -78 deg C, 43 min
2: 1.) o-nitrophenyl selenocyanate, tri-n-butylphosphine, 2.) aq. hydrogen peroxide / 1.) THF, 0 deg C, 15 min; room temperature, 45 min, 2.) 0 deg C, 20 min; 30 min
With
sodium tetrahydroborate; ortho-nitrophenyl selenocyanate; tributylphosphine; dihydrogen peroxide; ozone;
In
methanol;
DOI:10.1021/ja00343a030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 62 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1.) 0 deg C, 45 min, 2.) room temperature, 30 min
2: 1.) ozone, 2.) sodium borohydride / methanol / 1.) -78 deg C, 43 min
3: 1.) o-nitrophenyl selenocyanate, tri-n-butylphosphine, 2.) aq. hydrogen peroxide / 1.) THF, 0 deg C, 15 min; room temperature, 45 min, 2.) 0 deg C, 20 min; 30 min
With
sodium tetrahydroborate; ortho-nitrophenyl selenocyanate; tributylphosphine; dihydrogen peroxide; ozone; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja00343a030
