Technology Process of (5S,6S)-6-(4-methoxybenzyloxy)-12,12-dimethyl-11,11-diphenyl-5-vinyl-2,4,10-trioxa-11-silatri decane
There total 8 articles about (5S,6S)-6-(4-methoxybenzyloxy)-12,12-dimethyl-11,11-diphenyl-5-vinyl-2,4,10-trioxa-11-silatri decane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: C48H54N6O4; potassium carbonate; potassium osmate(VI) dihydrate; C6FeN6(3-)*2K(1+); methanesulfonamide / tert-butyl alcohol; water / 24 h / 0 °C
2: camphor-10-sulfonic acid / dichloromethane / 3 h / 20 °C
3: diisobutylaluminium hydride / dichloromethane / 0.5 h / 0 °C
4: Dess-Martin periodane / dichloromethane / 2 h / 20 °C
5: sodium hexamethyldisilazane / tetrahydrofuran / 4 h / -78 - 0 °C
6: acetic acid / water / 3 h / 50 °C
7: N-ethyl-N,N-diisopropylamine / 2 h / 0 °C
8: sodium hydride / tetrahydrofuran / 6 h / 0 °C
With
potassium osmate(VI) dihydrate; methanesulfonamide; camphor-10-sulfonic acid; C48H54N6O4; C6FeN6(3-)*2K(1+); sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; potassium carbonate; Dess-Martin periodane; acetic acid; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2013.04.069
- Guidance literature:
-
Multi-step reaction with 6 steps
1: diisobutylaluminium hydride / dichloromethane / 0.5 h / 0 °C
2: Dess-Martin periodane / dichloromethane / 2 h / 20 °C
3: sodium hexamethyldisilazane / tetrahydrofuran / 4 h / -78 - 0 °C
4: acetic acid / water / 3 h / 50 °C
5: N-ethyl-N,N-diisopropylamine / 2 h / 0 °C
6: sodium hydride / tetrahydrofuran / 6 h / 0 °C
With
sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; Dess-Martin periodane; acetic acid; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.tetlet.2013.04.069
