3-Methyl-1H-pyrazolo[4,3-b]pyridine

Base Information

Chemical Name:3-Methyl-1H-pyrazolo[4,3-b]pyridine
CAS No.:194278-45-0
Molecular Formula:C7H7 N3
Molecular Weight:133.153
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90442632
Wikidata:Q82260015
Mol file:194278-45-0.mol

Synonyms:3-Methyl-1H-pyrazolo[4,3-b]pyridine;194278-45-0;3-methyl-2H-pyrazolo[4,3-b]pyridine;1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI);MFCD08062968;1H-PYRAZOLO[4,3-B]PYRIDINE, 3-METHYL-;SCHEMBL254887;SCHEMBL15074585;DTXSID90442632;AKOS006285733;AM85002;CS-W021962;PB27871;1h-pyrazolo[4,3-b]pyridine,3-methyl-;DS-11316;SY097019;FT-0684846;EN300-197166;A880207

Suppliers and Price of 3-Methyl-1H-pyrazolo[4,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methyl-1H-pyrazolo[4,3-b]pyridine
500mg
$ 130.00

SynQuest Laboratories
3-Methyl-1H-pyrazolo[4,3-b]pyridine
250 mg
$ 360.00

SynQuest Laboratories
3-Methyl-1H-pyrazolo[4,3-b]pyridine
1 g
$ 888.00

Matrix Scientific
3-Methyl-1H-pyrazolo[4,3-b]pyridine >95%
500mg
$ 698.00

Matrix Scientific
3-Methyl-1H-pyrazolo[4,3-b]pyridine >95%
250mg
$ 435.00

Crysdot
3-Methyl-1H-pyrazolo[4,3-b]pyridine 95+%
10g
$ 467.00

Crysdot
3-Methyl-1H-pyrazolo[4,3-b]pyridine 95+%
5g
$ 235.00

ChemScene
3-Methyl-1H-pyrazolo[4,3-b]pyridine 98.76%
1g
$ 60.00

Chemenu
3-methyl-1H-pyrazolo[4,3-b]pyridine 95+%
1g
$ 97.00

American Custom Chemicals Corporation
3-METHYL-1H-PYRAZOLO-[4,3-B]PYRIDINE 95.00%
5MG
$ 505.96

Total 30 raw suppliers

Chemical Property of 3-Methyl-1H-pyrazolo[4,3-b]pyridine

Chemical Property:

Refractive Index:1.68
PSA：41.57000
Density:1.273g/cm³
LogP:1.26630
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:133.063997236
Heavy Atom Count:10
Complexity:126

Purity/Quality:

99%, ^*data from raw suppliers

3-Methyl-1H-pyrazolo[4,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=NN1)C=CC=N2

Technology Process of 3-Methyl-1H-pyrazolo[4,3-b]pyridine

There total 5 articles about 3-Methyl-1H-pyrazolo[4,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 87674-20-2
1-(3-fluoropyridin-2-yl)ethanone

: 194278-45-0
3-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: With hydrazine hydrate; at 130 ℃; for 3h; Microwave irradiation;

Reference yield: 43.0%

: 194278-45-0
3-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: With hydrazine; at 120 ℃;

Reference yield:

: 194278-44-9
1-(3-nitropyridin-2-yl)ethanone

: 194278-45-0
3-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.22 g / H₂ / 10percent Pd/C / ethanol / 24 h / Ambient temperature

2: 1.) NaNO₂, aq. H₂SO₄, 2.) SnCl₂, aq. HCl / 1.) a) 0 deg C, 30 min, b) RT, 15 min, 2.) a) 0 deg C, 20 min, b) RT, 20 min

With hydrogenchloride; sulfuric acid; hydrogen; tin(ll) chloride; sodium nitrite; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm970265x