1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine

Base Information

Chemical Name:1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine
CAS No.:193690-71-0
Molecular Formula:C₉H₁₂N₄
Molecular Weight:176.221
Hs Code.:
DSSTox Substance ID:DTXSID30444296
Nikkaji Number:J848.051F
Wikidata:Q82262402
Mol file:193690-71-0.mol

Synonyms:1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine;193690-71-0;1,6,7-TRIMETHYLIMIDAZO[4,5-C]PYRIDIN-2-AMINE;DTXSID30444296

Suppliers and Price of 1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine

Chemical Property:

Boiling Point:389.1±34.0 °C(Predicted)
PKA:8.66±0.30(Predicted)
PSA：57.46000
Density:1.30±0.1 g/cm3(Predicted)
LogP:1.09740
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:176.106196400
Heavy Atom Count:13
Complexity:196

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CN=C1C)N=C(N2C)N

Technology Process of 1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine

There total 7 articles about 1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22710-07-2,166521-76-2
2,3-dimethylpyridine 1-oxide

: 193690-71-0
1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 7 steps

1: 78 percent / H₂SO₄, HNO₃ / 5 h / 100 °C

2: 94 percent / H₂, gl. AcOH / 10percent Pd/C / 12 h / 60 °C / 2585.7 Torr

3: 60 percent / Na₂CO₃ / acetone / 3 h / Ambient temperature

4: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature

5: 18 percent / H₂SO₄, fuming HNO₃ / 3 h / 110 °C

6: H₂ / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature

7: ethanol / 18 h / 110 °C

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; nitric acid; sodium carbonate; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1002/jhet.5570340303

Reference yield:

: 37699-43-7
2,3-dimethyl-4-nitropyridine N-oxide

: 193690-71-0
1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 6 steps

1: 94 percent / H₂, gl. AcOH / 10percent Pd/C / 12 h / 60 °C / 2585.7 Torr

2: 60 percent / Na₂CO₃ / acetone / 3 h / Ambient temperature

3: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature

4: 18 percent / H₂SO₄, fuming HNO₃ / 3 h / 110 °C

5: H₂ / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature

6: ethanol / 18 h / 110 °C

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; nitric acid; sodium carbonate; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1002/jhet.5570340303

Reference yield:

: 122475-57-4
4-amino-2,3-dimethylpyridine

: 193690-71-0
1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / Na₂CO₃ / acetone / 3 h / Ambient temperature

2: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature

3: 18 percent / H₂SO₄, fuming HNO₃ / 3 h / 110 °C

4: H₂ / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature

5: ethanol / 18 h / 110 °C

With lithium aluminium tetrahydride; sulfuric acid; hydrogen; nitric acid; sodium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1002/jhet.5570340303