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Usage

Uses

Used in Pharmaceutical Industry:
4-Pyridinamine,2,3-dimethyl-(9CI) is used as a synthetic intermediate for the development of various compounds with potent biological activities. One of its significant applications is in the synthesis of polymethylated γ-carbolines, which have demonstrated strong anti-bovine viral diarrhea virus (BVDV) activity. BVDV is a significant pathogen affecting the cattle industry, and the development of effective antiviral agents is crucial for controlling the spread of the disease and improving animal health.
In addition to its role in the synthesis of antiviral compounds, 4-Pyridinamine,2,3-dimethyl-(9CI) may also be utilized in the development of other pharmaceutical products with potential therapeutic applications. Its unique chemical structure allows for further functionalization and modification, making it a valuable starting material for the design and synthesis of novel drugs targeting various diseases and conditions.
Used in Chemical Synthesis:
Beyond its applications in the pharmaceutical industry, 4-Pyridinamine,2,3-dimethyl-(9CI) can also be employed as a key intermediate in the synthesis of various chemical compounds for different purposes. Its reactivity and functional groups make it a suitable candidate for use in the development of new materials, dyes, and other specialty chemicals. The compound's versatility in chemical reactions allows for the creation of a wide range of products with diverse applications across various industries.

InChI:InChI=1/C7H10N2/c1-5-6(2)9-4-3-7(5)8/h3-4H,1-2H3,(H2,8,9)

Upstream product

• 37699-43-7 2,3-dimethyl-4-nitropyridine N-oxide 
• 22710-07-2 2,3-dimethylpyridine 1-oxide 

Downstream Products

• 1144040-10-7 C₁₃H₁₃BrN₂ 
• 193690-71-0 1,6,7-Trimethyl-1H-imidazo[4,5-c]pyridin-2-ylamine 
• 193690-67-4 2,3-dimethyl-4-methylaminopyridine 

Relevant academic research and scientific papers

Applications of TiCl3 as a Diagnostic Reagent for the Detection of Nitro- and N-Oxide-Containing Compounds as Potentially Mutagenic Impurities Using Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry

The ICH has strict guidelines for limiting the presence of potentially mutagenic impurities (PMIs) in marketed drugs. Therefore, it is important to fully characterize and quantitate all possible PMIs that could arise during the process of synthesizing and developing a drug. Two important and prevalent examples of PMIs are compounds containing N-oxide and nitro functional groups. TiCl3 derivatization is an established method for determining the presence or absence of N-oxide metabolites by reduction to the corresponding amine. In this study, we demonstrate a novel application of TiCl3 reduction combined with high-resolution UHPLC/HRMS to analyze PMIs. The results indicate that a variety of N-oxide- and nitro-containing compounds can be readily characterized by this facile platform method. In addition, we show that this chemical derivatization method can be utilized to enhance the ionization of nitro-containing compounds for LC/MS analysis.

Polymethylated γ-carbolines with potent anti-bovine viral diarrhea virus (BVDV) activity

Several anti-BVDV agents with a polymethylated γ-carboline skeleton were synthesized, and their anti-BVDV activity was evaluated. The most potent antiviral agent, SK3M4M5M (20), was synthesized by Pd-catalyzed Buchwald-Hartwig amination reaction followed

Syntheses of five potential heterocyclic amine food mutagens

The syntheses of the potential heterocyclic amine food mutagens, 3,5,7- trimethyl-2-aminoimidazo[4,5-b]pyridine, 1,4,7-trimethyl-2-aminoimidazo[4,5- c]pyridine, 1,6,7-trimethyl-2-aminoimidazo[4,5-c]-pyridine, 3,4,6-trimethyl- 2-aminoimidazo[4,5-c]pyridine, and 1,4,6-trimethyl-7-aminoimidazo[4,5-c]- pyridine are described.

4-AMINOPYRIDINE-2,3-DICARBOXYLIC ACID FROM CLITOCYBE ACROMELALGA

A new pyridine derivative, 4-aminopyridine-2,3-dicarboxylic acid, was isolated from Clitocybe acromelalga, and its structure was determined by spectral and synthetic methods. - Keywords: Clitocybe acromelalga; Tricholomataceae; Basidiomycetes; 4-aminopyridine-2,3-dicarboxylic acid.