Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-

Base Information

Chemical Name:Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-
CAS No.:193545-89-0
Molecular Formula:C23H38 N2 O2
Molecular Weight:374.56
Hs Code.:
Mol file:193545-89-0.mol

Synonyms:Decanamide,N-[2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-, [R-(R*,R*)]-

Suppliers and Price of Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-[(1R,2R)-2-HYDROXY-2-PHENYL-1-(1-PYRROLIDINYLMETHYL)ETHYL]DECANAMIDE 95.00%
5MG
$ 505.81

Total 2 raw suppliers

Chemical Property of Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.527
Boiling Point:563.479°C at 760 mmHg
Flash Point:294.582°C
PSA：52.57000
Density:1.028g/cm³
LogP:4.77010

Purity/Quality:

95% ^*data from raw suppliers

N-[(1R,2R)-2-HYDROXY-2-PHENYL-1-(1-PYRROLIDINYLMETHYL)ETHYL]DECANAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]-

There total 4 articles about Decanamide, N-[(1R,2R)-2-hydroxy-2-phenyl-1-(1-pyrrolidinylmethyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.2%

: 1956-09-8
4-nitrophenyl decanoate

: 193545-88-9
(1R,2R)-2-Amino-3-pyrrolidino-1-phenyl-1-propanol

: 193545-89-0
(1R,2R)-2-decanoylamino-3-pyrrolidino-1-phenyl-1-propanol

Guidance literature:: With benzotriazol-1-ol; In pyridine;
DOI:10.1021/jo980951j

Reference yield:

: 218766-22-4
(4R,5R)-5-Phenyl-4-pyrrolidin-1-ylmethyl-oxazolidin-2-one

: 193545-89-0
(1R,2R)-2-decanoylamino-3-pyrrolidino-1-phenyl-1-propanol

Guidance literature:: Multi-step reaction with 2 steps

1: 80.7 percent / aq. KOH / methanol / 16 h / 70 °C

2: 74.2 percent / 1-hydroxybenzotriazole / pyridine

With potassium hydroxide; benzotriazol-1-ol; In pyridine; methanol;
DOI:10.1021/jo980951j

Reference yield:

: 218766-10-0
(1R,2R)-2-(Benzhydrylidene-amino)-3-(tert-butyl-dimethyl-silanyloxy)-1-phenyl-propan-1-ol

: 193545-89-0
(1R,2R)-2-decanoylamino-3-pyrrolidino-1-phenyl-1-propanol

Guidance literature:: Multi-step reaction with 7 steps

1: 80 percent / aq. pyridinium p-toluenesulfonate / tetrahydrofuran / 4.5 h

2: 72.8 percent / Et₃N / CH₂Cl₂ / 5 h / 0 °C

3: 95 percent / aq. HF / acetonitrile / 1.25 h / Ambient temperature

4: 98.5 percent / pyridine / 4 h / Ambient temperature

5: 70.1 percent / tetrahydrofuran / 11 h / Heating

6: 80.7 percent / aq. KOH / methanol / 16 h / 70 °C

7: 74.2 percent / 1-hydroxybenzotriazole / pyridine

With pyridine; potassium hydroxide; hydrogen fluoride; pyridinium p-toluenesulfonate; benzotriazol-1-ol; triethylamine; In tetrahydrofuran; pyridine; methanol; dichloromethane; acetonitrile;
DOI:10.1021/jo980951j