6-Methoxypyridine-3-carbonyl chloride

Base Information

Chemical Name:6-Methoxypyridine-3-carbonyl chloride
CAS No.:193538-78-2
Molecular Formula:C7H6 Cl N O2
Molecular Weight:171.583
Hs Code.:
DSSTox Substance ID:DTXSID70591374
Wikidata:Q82485128
Mol file:193538-78-2.mol

Synonyms:193538-78-2;6-Methoxypyridine-3-carbonyl chloride;6-Methoxynicotinoyl chloride;3-Pyridinecarbonyl chloride, 6-methoxy- (9CI);3-PYRIDINECARBONYL CHLORIDE, 6-METHOXY-;3-Pyridinecarbonylchloride, 6-methoxy-;6-Methoxynicotinoylchloride;SCHEMBL2154730;DTXSID70591374;IFGABUQRWWPAIC-UHFFFAOYSA-N;DB-333620;3-Pyridinecarbonyl chloride,6-methoxy-(9ci);EN300-313561

Suppliers and Price of 6-Methoxypyridine-3-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-methoxypyridine-3-carbonylchloride
250mg
$ 330.00

Total 5 raw suppliers

Chemical Property of 6-Methoxypyridine-3-carbonyl chloride

Chemical Property:

Boiling Point:267.1±20.0 °C(Predicted)
PKA:0.80±0.10(Predicted)
PSA：39.19000
Density:1.289±0.06 g/cm3(Predicted)
LogP:1.46920
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:171.0087061
Heavy Atom Count:11
Complexity:151

Purity/Quality:

99% ^*data from raw suppliers

6-methoxypyridine-3-carbonylchloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=NC=C(C=C1)C(=O)Cl

Technology Process of 6-Methoxypyridine-3-carbonyl chloride

There total 3 articles about 6-Methoxypyridine-3-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66572-55-2
6-methoxynicotinic acid

: 193538-78-2
6-methoxynicotinic acid chloride

Guidance literature:: With thionyl chloride; for 3.5h; Heating;
DOI:10.1002/hlca.19910740218

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 193538-78-2
6-methoxynicotinic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: Na / 15 h / Heating

2: SOCl₂ / 3.5 h / Heating

With thionyl chloride; sodium;
DOI:10.1002/hlca.19910740218

Reference yield:

: 26218-80-4
6-methoxy-nicotinic acid methyl ester

: 193538-78-2
6-methoxynicotinic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; methanol / 6 h / Reflux

2: thionyl chloride / 4 h / Reflux

With methanol; thionyl chloride; sodium hydroxide;
DOI:10.1080/14756366.2020.1868450