26218-80-4Relevant articles and documents
ABNORMAL NUCLEOPHILIC SUBSTITUTION OF 3-TRICHLOROMETHYLPYRIDINES BY METHOXIDE
Dainter, Ronald S.,Suschitzky, Hans,Wakefield, Basil J.,Hughes, Nigel,Nelson, Anthony J.
, p. 5693 - 5696 (1984)
3-Trichloromethylpyridine and its α-chlorinated derivatives behave as ambident electrophilic substrates towards methoxide which attacks an α-position and the trichloromethyl group.
Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide
Ma, Cong,Zhao, Chuan-Qi,Xu, Xue-Tao,Li, Zhao-Ming,Wang, Xiang-Yang,Zhang, Kun,Mei, Tian-Sheng
, p. 2464 - 2467 (2019/04/10)
The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.
MULTIPLE PATHS FOR PHOTOALKYLATION OF PYRIDINECARBOXYLIC ESTERS IN ALCOHOLS
Sugiyama, Toru,Tobita, Estuo,Takagi, Kyoko,Sato, Michitsugu,Kumagai, Yasuyuki,et al.
, p. 131 - 134 (2007/10/02)
Photochemical substitution of ring hydrogen of pyridinecarboxylic esters by alkyl groups derived from solvent alcohols occurs in several paths: 1) alkylation initiated by excited carbonyl moiety of the ester group and 2) alkylation initiated by the excitation of the ?-electronic system of the pyridine ring.In the photoreaction of methyl 3-pyridinecarboxylate in acidic methanol, three types of excited state (two triplet states for alkylation and a singlet state for alkoxylation) contribute simultaneously.
