(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Base Information

Chemical Name:(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene
CAS No.:1380003-25-7
Molecular Formula:C₂₀H₃₀O₃Si
Molecular Weight:346.542
Hs Code.:

Synonyms:(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Suppliers and Price of (1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

There total 2 articles about (1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1380003-23-5
(1E,3E)-1-[2-(acetoxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

: 1380003-25-7
(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Guidance literature:: With water; potassium carbonate; In methanol; at 25 ℃; for 2h; Inert atmosphere;
DOI:10.1002/chem.201103360

Reference yield:

: 853955-59-6
dimethyl-[2-(2-acetoxymethyl)phenyl]-silane

: 1380003-25-7
(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

Guidance literature:: Multi-step reaction with 2 steps

1: platinum⁽⁰⁾-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; tri-tert-butyl phosphine / toluene; xylenes / 10 h / 25 °C / Inert atmosphere

2: water; potassium carbonate / methanol / 2 h / 25 °C / Inert atmosphere

With platinum⁽⁰⁾-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; tri-tert-butyl phosphine; water; potassium carbonate; In methanol; toluene; xylenes;
DOI:10.1002/chem.201103360

Reference yield: 83.0%

: C₁₄H₂₁I

: 1380003-25-7
(1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene

: 138842-95-2
trans-tetrahydropyran-2-yl retinyl ether

Guidance literature:: (1E,3E)-1-[2-(hydroxymethyl)phenyl]dimethylsilyl-3-methyl-5-(tetrahydropyran-2-yloxy)penta-1,3-diene; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere; Darkness;

C₁₄H₂₁I; With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; at 20 ℃; for 1h; stereospecific reaction; Inert atmosphere; Darkness;
DOI:10.1002/chem.201103360