2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone

Base Information

• Chemical Name: 2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone
• CAS No.: 165449-47-8
• Molecular Formula: C₉H₁₄N₂O₂
• Molecular Weight: 182.222
• Mol file: 165449-47-8.mol

Synonyms:2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone

Chemical Property of 2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone

There total 1 articles about 2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclohexenone (930-68-7) + ethylhydrazine carboxylate (4114-31-2) → 2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone (165449-47-8)

Guidance literature:

With acetic acid; In ethanol; for 24h; Ambient temperature;

DOI:10.1021/jo00099a037

Reference yield:

2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone (165449-47-8) → 2-methoxycyclohex-2-en-1-one (23740-37-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) Br₂, 2.) 1 N aq. NaHCO₃ / 1.) CH₂Cl₂, -50 deg C to 0 deg C, 2.) r.t., 1 h

2: concd H₂SO₄ / Ambient temperature

3: 1 N aq. HCl, 38percent aq. CH₂O / 1 h / Ambient temperature

4: DBU / diethyl ether

With hydrogenchloride; formaldehyd; sulfuric acid; bromine; sodium hydrogencarbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether;

DOI:10.1021/jo00099a037

Reference yield:

2-Cyclohexen-1-one (ethoxycarbonyl)hydrazone (165449-47-8) → C9H13BrN2O2

Guidance literature:

With bromine; sodium hydrogencarbonate; Yield given. Multistep reaction; 1.) CH₂Cl₂, -50 deg C to 0 deg C, 2.) r.t., 1 h;

DOI:10.1021/jo00099a037

upstream raw materials:

cyclohexenone

ethylhydrazine carboxylate

Downstream raw materials:

2-methoxycyclohex-2-en-1-one

3-bromo-2-methoxycyclohexanone