N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide

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Chemical Name:N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide
CAS No.:942272-97-1
Molecular Formula:C₂₄H₂₆F₂N₆O₄S
Molecular Weight:532.571
Hs Code.:

Synonyms:N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide

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Chemical Property of N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide

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Technology Process of N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide

There total 1 articles about N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-({3-[(tetrahydro-pyran-4-yl)-(2,2,2-trifluoro-acetyl)-amino]-pyridine-4-carbonyl}-amino)-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole-1-carboxylic acid ethyl ester hydrochloride

: 210532-25-5
3,5-difluorobenzenesulfonyl chloride

: 942272-97-1
N-[5-(3,5-difluoro-benzenesulfonyl)-6,6-dimethyl-1,4,5,6-tetrahydro-pyrrolo[3,4-c]pyrazol-3-yl]-3-(tetrahydro-pyran-4-ylamino)-isonicotinamide

Guidance literature:: 3-({3-[(tetrahydro-pyran-4-yl)-(2,2,2-trifluoro-acetyl)-amino]-pyridine-4-carbonyl}-amino)-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole-1-carboxylic acid ethyl ester hydrochloride; 3,5-difluorobenzenesulfonyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 4h;

With methanol; triethylamine; In dichloromethane; at 60 ℃; for 2h;