N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

Base Information

Chemical Name:N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine
CAS No.:1032316-04-3
Molecular Formula:C₂₈H₃₀N₂O₂
Molecular Weight:426.558
Hs Code.:

Synonyms:N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

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Chemical Property of N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

Chemical Property:

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Technology Process of N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

There total 5 articles about N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₂₀BrNO₂

: 109-89-7
diethylamine

: 1032316-04-3
N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

Guidance literature:: C₂₄H₂₀BrNO₂; diethylamine; In benzene; for 1h; Heating / reflux;

With hydrogenchloride; In water; ethyl acetate;

With sodium hydrogencarbonate; In water; pH=7 - 8;

Reference yield:

: 1032315-99-3
6-methoxy-2-m-tolylquinolin-4(1H)-one

: 1032316-04-3
N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 20 °C

2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / benzene / 1.5 h / 20 - 80 °C

3.1: benzene / 1 h / Heating / reflux

3.3: pH 7 - 8

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sodium hydride; In N,N-dimethyl-formamide; benzene;

Reference yield:

: 585-74-0
3-Methylacetophenone

: 1032316-04-3
N-{[3-(4-(benzyloxy)-6-methoxyquinolin-2-yl)phenyl]methyl}-N-ethylethanamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / toluene / 0.5 h / Heating / reflux

1.2: 20 °C

2.1: PPA; Polyphosphoric acid (PPA) / 130 °C

2.2: 20 °C

3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

3.2: 20 °C

4.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / benzene / 1.5 h / 20 - 80 °C

5.1: benzene / 1 h / Heating / reflux

5.3: pH 7 - 8

With N-Bromosuccinimide; PPA; Polyphosphoric acid (PPA); 2,2'-azobis(isobutyronitrile); sodium hydride; In N,N-dimethyl-formamide; toluene; benzene;