Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)

Base Information

Chemical Name:Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)
CAS No.:192430-31-2
Molecular Formula:C₈H₁₆N₂O₃
Molecular Weight:188.227
Hs Code.:
Mol file:192430-31-2.mol

Synonyms:Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)

Suppliers and Price of Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)

Chemical Property:

PSA：61.80000
LogP:0.43300

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI)

There total 1 articles about Carbamic acid, [2-(hydroxymethyl)-1-pyrrolidinyl]-, ethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 541-41-3
chloroformic acid ethyl ester

: (1-Amino-pyrrolidin-2-yl)-methanol

: 192430-31-2
(2-Hydroxymethyl-pyrrolidin-1-yl)-carbamic acid ethyl ester

Guidance literature:: With alkali hydrocarbonate; In diethyl ether; water;
DOI:10.3987/com-97-7760

Reference yield: 76.0%

: 192430-31-2
(2-Hydroxymethyl-pyrrolidin-1-yl)-carbamic acid ethyl ester

: 192430-29-8
1-methylamino-2-hydroxymethylpyrrolidine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 70 ℃; for 18h;
DOI:10.3987/com-97-7760

Reference yield:

: 192430-31-2
(2-Hydroxymethyl-pyrrolidin-1-yl)-carbamic acid ethyl ester

: 1-(2-Hydroxymethyl-pyrrolidin-1-yl)-1,2-dimethyl-3-phenyl-isothiourea

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / LiAlH₄ / tetrahydrofuran / 18 h / 70 °C

2: diethyl ether

3: 1.) MeI; 2.) KOH / 1.) MeOH, r.t., 5-6 h; 2.) MeOH, r.t., overnight

With potassium hydroxide; lithium aluminium tetrahydride; methyl iodide; In tetrahydrofuran; diethyl ether;
DOI:10.3987/com-97-7760