4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester

Base Information

• Chemical Name: 4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester
• CAS No.: 1069112-04-4
• Molecular Formula: C₁₉H₁₉NO₆
• Molecular Weight: 357.363
• Mol file: 1069112-04-4.mol

Synonyms:4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester

Chemical Property of 4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester

There total 1 articles about 4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethanol (64-17-5) + 5-[2-(5-benzyloxy-2-nitrophenyl)-1-hydroxy-ethylidene]-2,2-dimethyl-[1,3]dioxane-4,6-dione (1069111-99-4) → 4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester (1069112-04-4)

Guidance literature:

for 5h; Heating;

DOI:10.1016/j.tet.2008.07.045

Reference yield: 92.0%

4-(5-benzyloxy-2-nitrophenyl)-3-oxobutyric acid ethyl ester (1069112-04-4) → (5-benzyloxy-1H-indol-2-yl)-acetic acid ethyl ester (1069112-11-3)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; for 2h;

DOI:10.1016/j.tet.2008.07.045

upstream raw materials:

ethanol

5-[2-(5-benzyloxy-2-nitrophenyl)-1-hydroxy-ethylidene]-2,2-dimethyl-[1,3]dioxane-4,6-dione

Downstream raw materials:

(5-benzyloxy-1H-indol-2-yl)-acetic acid ethyl ester