(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

Base Information

Chemical Name:(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid
CAS No.:1141895-98-8
Molecular Formula:C₂₁H₂₁NO₅
Molecular Weight:367.401
Hs Code.:

Synonyms:(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

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Technology Process of (S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

There total 4 articles about (S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

: 337518-86-2
(S)-tert-butyl 3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoate

: 1141895-98-8
(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 48h;

Reference yield:

: 136159-65-4
(R)-4-benzyl-3-(3-phenyl-propionyl)-oxazolidin-2-one

: 1141895-98-8
(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -70 - 20 °C

2: trifluoroacetic acid / dichloromethane / 48 h

With trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 1141895-98-8
(S)-3-benzyl-4-((R)-4-benzyl-2-oxooxazolidin-3-yl)-4-oxobutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; dmap / dichloromethane / 2 h / 0 °C

2: lithium diisopropyl amide / tetrahydrofuran / 1 h / -70 - 20 °C

3: trifluoroacetic acid / dichloromethane / 48 h

With dmap; triethylamine; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;