(R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole

Base Information

Chemical Name:(R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole
CAS No.:191330-82-2
Molecular Formula:C₁₅H₁₂BrNO
Molecular Weight:302.17
Hs Code.:
DSSTox Substance ID:DTXSID20461391
Nikkaji Number:J1.486.728G
Wikidata:Q82285717
Mol file:191330-82-2.mol

Synonyms:(R)-2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE;191330-82-2;(4R)-2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDRO-1,3-OXAZOLE;CTK4E0628;DTXSID20461391;BS-50845;F73115;4-Isoxazolecarboxylic acid, 3-phenyl-5-(trifluoromethyl)-, ethyl ester

Suppliers and Price of (R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE 95.00%
5MG
$ 500.52

Ambeed
(R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole 97%
100mg
$ 122.00

Total 6 raw suppliers

Chemical Property of (R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole

Chemical Property:

PSA：21.59000
LogP:3.40280
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:301.01023
Heavy Atom Count:18
Complexity:312

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-(2-BROMOPHENYL)-4-PHENYL-4,5-DIHYDROOXAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N=C(O1)C2=CC=CC=C2Br)C3=CC=CC=C3
Isomeric SMILES:C1[C@H](N=C(O1)C2=CC=CC=C2Br)C3=CC=CC=C3

Technology Process of (R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole

There total 11 articles about (R)-2-(2-Bromophenyl)-4-phenyl-4,5-dihydrooxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 7154-66-7
2-bromobenzoic acid chloride

: 20989-17-7,56613-80-0,71006-16-1,7568-92-5,188586-38-1
Phenylglycinol

: 153233-81-9,191330-82-2
2-(2-bromophenyl)-4-phenyl-4,5-dihydrooxazole

Guidance literature:: 2-bromobenzoic acid chloride; Phenylglycinol; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 24h;

With methanesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; for 23h;
DOI:10.1039/c8cc06649c

Reference yield: 63.0%

: (S)-2-bromo-N-(2-hydroxy-1-phenylethyl)benzamide

: 321848-64-0,153233-81-9,191330-82-2
(4S)-2-(2-bromophenyl)-4-phenyl-4,5-dihydro-1,3-oxazole

Guidance literature:: With Vilsmeier reagent; In pyridine; at 20 ℃;
DOI:10.1021/jo000664r

Reference yield: 62.0%

: 56613-80-0
D-2-phenylglycinol

: 6630-33-7
ortho-bromobenzaldehyde

: 153233-81-9,191330-82-2
(4R)-2-(2-bromophenyl)-4-phenyl-4,5-dihydro-1,3-oxazole

Guidance literature:: D-2-phenylglycinol; ortho-bromobenzaldehyde; In toluene; at 20 ℃; for 24h; Molecular sieve;

With potassium phosphate; N-Bromosuccinimide; In toluene; at 20 ℃; for 3.08333h;
DOI:10.1055/s-0030-1260124