1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Base Information

Chemical Name:1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one
CAS No.:847650-91-3
Molecular Formula:C₉H₁₀N₂O₅
Molecular Weight:226.189
Hs Code.:

Synonyms:1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Suppliers and Price of 1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

There total 4 articles about 1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 58-96-8
uridine

: 847650-91-3
1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Guidance literature:: With sodium hydrogencarbonate; benzoic acid anhydride; In N,N-dimethyl-formamide; at 100 ℃; for 4h;
DOI:10.1080/15257770701530525

Reference yield:

: ⁽¹⁴⁾

: 847650-91-3
1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Guidance literature:: With sodium hydride; trimethyloxosulfonium chloride; In tetrahydrofuran;
DOI:10.1021/ja00743a032

Reference yield:

: 54618-06-3
5′-O-benzoyluridine

: 847650-91-3
1-((2R,4S,5R)-3,4-anhydro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1H,1'H-thiocarbonyl-bis-imidazole

2: NaH, Me₃S(O)Cl / tetrahydrofuran

With sodium hydride; trimethyloxosulfonium chloride; 1,1'-Thiocarbonyldiimidazole; In tetrahydrofuran;
DOI:10.1021/ja00743a032