3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

Base Information

• Chemical Name: 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate
• CAS No.: 1448784-23-3
• Molecular Formula: C₇H₇O₃S*C₁₉H₁₆NO₂S
• Molecular Weight: 493.604
• Mol file: 1448784-23-3.mol

Synonyms:3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

Chemical Property of 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

There total 4 articles about 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

3-(2-methylbenzo[d]thiazol-6-yl)-2H-chromen-2-one (108896-13-5) + ethyl ester of p-toluenesulfonic acid (80-40-0) → 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (1448784-23-3)

Guidance literature:

at 140 ℃; for 4h;

DOI:10.1016/j.mencom.2013.07.011

Reference yield:

2-Methylbenzothiazole (120-75-2) → 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (1448784-23-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: nitric acid; sulfuric acid

2.1: hydrazine hydrate; iron(III) chloride / isopropyl alcohol

3.1: sodium nitrite; hydrogenchloride / water / -5 °C

3.2: 1.5 h / 0 °C

4.1: 4 h / 140 °C

With hydrogenchloride; iron(III) chloride; sulfuric acid; nitric acid; hydrazine hydrate; sodium nitrite; In water; isopropyl alcohol; 3.2: |Meerwein Arylation;

DOI:10.1016/j.mencom.2013.07.011

Reference yield:

2-methyl-6-nitrobenzothiazole (2941-63-1) → 3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (1448784-23-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrazine hydrate; iron(III) chloride / isopropyl alcohol

2.1: sodium nitrite; hydrogenchloride / water / -5 °C

2.2: 1.5 h / 0 °C

3.1: 4 h / 140 °C

With hydrogenchloride; iron(III) chloride; hydrazine hydrate; sodium nitrite; In water; isopropyl alcohol; 2.2: |Meerwein Arylation;

DOI:10.1016/j.mencom.2013.07.011

upstream raw materials:

2-Methylbenzothiazole

3-(2-methylbenzo[d]thiazol-6-yl)-2H-chromen-2-one

ethyl ester of p-toluenesulfonic acid

2-methyl-6-nitrobenzothiazole

Downstream raw materials:

3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

3-ethyl-2-{(1E,3E,5E)-5-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]penta-1-dienyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate