3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

Base Information

• Chemical Name: 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate
• CAS No.: 108878-40-6
• Molecular Formula: C₇H₇O₃S*C₃₉H₂₉N₂O₄S₂
• Molecular Weight: 824.999
• Mol file: 108878-40-6.mol

Synonyms:

Chemical Property of 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

There total 6 articles about 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (1448784-23-3) + orthoformic acid triethyl ester (122-51-0) → 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (108878-40-6,1448784-25-5)

Guidance literature:

With pyridine; for 0.25h; Heating;

DOI:10.1016/j.mencom.2013.07.011

Reference yield:

2-Methylbenzothiazole (120-75-2) → 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (108878-40-6,1448784-25-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: nitric acid; sulfuric acid

2.1: hydrazine hydrate; iron(III) chloride / isopropyl alcohol

3.1: sodium nitrite; hydrogenchloride / water / -5 °C

3.2: 1.5 h / 0 °C

4.1: 4 h / 140 °C

5.1: pyridine / 0.25 h / Heating

With pyridine; hydrogenchloride; iron(III) chloride; sulfuric acid; nitric acid; hydrazine hydrate; sodium nitrite; In water; isopropyl alcohol; 3.2: |Meerwein Arylation;

DOI:10.1016/j.mencom.2013.07.011

Reference yield:

2-methyl-6-nitrobenzothiazole (2941-63-1) → 3-ethyl-2-{(1E,3E)-3-[3-ethyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazol-2(3H)-ylidene]prop-1-enyl}-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate (108878-40-6,1448784-25-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: hydrazine hydrate; iron(III) chloride / isopropyl alcohol

2.1: sodium nitrite; hydrogenchloride / water / -5 °C

2.2: 1.5 h / 0 °C

3.1: 4 h / 140 °C

4.1: pyridine / 0.25 h / Heating

With pyridine; hydrogenchloride; iron(III) chloride; hydrazine hydrate; sodium nitrite; In water; isopropyl alcohol; 2.2: |Meerwein Arylation;

DOI:10.1016/j.mencom.2013.07.011

upstream raw materials:

2-Methylbenzothiazole

3-ethyl-2-methyl-6-(2-oxo-2H-chromen-3-yl)benzo[d]thiazolium tosylate

orthoformic acid triethyl ester

2-methyl-6-nitrobenzothiazole