Technology Process of Pd(II)-3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin
There total 8 articles about Pd(II)-3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3,13-bis(ethoxycarbonyl)-2,12-dimesityl-5-methoxy-8,8,18,18-tetramethylbacteriochlorin;
With
lithium diisopropyl amide;
In
tetrahydrofuran; n-heptane; ethylbenzene;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
palladium(II) bromide;
In
tetrahydrofuran; n-heptane; ethylbenzene;
at 60 ℃;
for 20h;
Time;
Inert atmosphere;
DOI:10.1021/ic301262k
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydride / diethyl ether; dimethyl sulfoxide; mineral oil; tetrahydrofuran / 2.5 h / Inert atmosphere
2.1: trichlorophosphate / dichloromethane / 19 h / 0 - 20 °C / Inert atmosphere
2.2: 0 °C / Inert atmosphere
3.1: propylamine; acetic acid / tetrahydrofuran; methanol / 3.25 h / 0 - 20 °C / Inert atmosphere
4.1: silica gel; sodium tetrahydroborate / chloroform; isopropyl alcohol / 0.67 h
5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 7 h / 20 °C / Inert atmosphere
6.1: sodium methylate / tetrahydrofuran / 1.25 h / 20 °C / Inert atmosphere
6.2: 20 °C / pH 6 / Inert atmosphere
7.1: trimethylsilyl trifluoromethanesulfonate; 2,6-di-tert-butylphenol / dichloromethane / 19 h / 20 °C
8.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0.17 h / 20 °C / Inert atmosphere
8.2: 20 h / 60 °C / Inert atmosphere
With
propylamine; sodium tetrahydroborate; 2,6-di-tert-butylphenol; trimethylsilyl trifluoromethanesulfonate; sodium methylate; silica gel; sodium hydride; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium diisopropyl amide; trichlorophosphate;
In
tetrahydrofuran; methanol; diethyl ether; n-heptane; dichloromethane; chloroform; ethylbenzene; dimethyl sulfoxide; isopropyl alcohol; mineral oil;
2.1: |Vilsmeier Reaction / 3.1: |Henry Nitro Aldol Condensation / 5.1: |Michael Addition / 6.2: |McMurry Reaction;
DOI:10.1021/ic301262k
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: trichlorophosphate / dichloromethane / 19 h / 0 - 20 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: propylamine; acetic acid / tetrahydrofuran; methanol / 3.25 h / 0 - 20 °C / Inert atmosphere
3.1: silica gel; sodium tetrahydroborate / chloroform; isopropyl alcohol / 0.67 h
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 7 h / 20 °C / Inert atmosphere
5.1: sodium methylate / tetrahydrofuran / 1.25 h / 20 °C / Inert atmosphere
5.2: 20 °C / pH 6 / Inert atmosphere
6.1: trimethylsilyl trifluoromethanesulfonate; 2,6-di-tert-butylphenol / dichloromethane / 19 h / 20 °C
7.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0.17 h / 20 °C / Inert atmosphere
7.2: 20 h / 60 °C / Inert atmosphere
With
propylamine; sodium tetrahydroborate; 2,6-di-tert-butylphenol; trimethylsilyl trifluoromethanesulfonate; sodium methylate; silica gel; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium diisopropyl amide; trichlorophosphate;
In
tetrahydrofuran; methanol; n-heptane; dichloromethane; chloroform; ethylbenzene; isopropyl alcohol;
1.1: |Vilsmeier Reaction / 2.1: |Henry Nitro Aldol Condensation / 4.1: |Michael Addition / 5.2: |McMurry Reaction;
DOI:10.1021/ic301262k
