{(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester

Base Information

• Chemical Name: {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester
• CAS No.: 743469-63-8
• Molecular Formula: C₃₃H₃₉NO₆
• Molecular Weight: 545.676
• Mol file: 743469-63-8.mol

Synonyms:{(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester

Chemical Property of {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester

There total 9 articles about {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-hexa-3,5-dien-1-ol (73670-87-8) → {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester (743469-63-8)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylformamide

2: 1.57 g / pyridine / 20 °C

With pyridine; In N,N-dimethyl-formamide;

DOI:10.1021/jo0100190

Reference yield:

Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester (743457-76-3) → {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester (743469-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / methanol / 3 h / 20 °C

2: 1.57 g / pyridine / 20 °C

With pyridine; potassium carbonate; In methanol;

DOI:10.1021/jo0100190

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) + ((R)-3,5-Dihydroxy-pentyl)-carbamic acid (E)-hexa-3,5-dienyl ester → {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester (743469-63-8)

Guidance literature:

With pyridine;

DOI:10.1081/NCN-100002332

upstream raw materials:

4,4'-dimethoxytrityl chloride

sorbic Acid

(E)-hexa-3,5-dien-1-ol

(E)-3,5-hexadienoic acid