Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester

Base Information

• Chemical Name: Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester
• CAS No.: 743457-76-3
• Molecular Formula: C₁₆H₂₅NO₆
• Molecular Weight: 327.378
• Mol file: 743457-76-3.mol

Synonyms:Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester

Chemical Property of Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester

There total 1 articles about Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-hexa-3,5-dien-1-ol (73670-87-8) → Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester (743457-76-3)

Guidance literature:

Multi-step reaction with 2 steps

1.2: Et₃N

DOI:10.1081/NCN-100002332

Reference yield:

Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester (743457-76-3) → {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester (743469-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / methanol / 3 h / 20 °C

2: 1.57 g / pyridine / 20 °C

With pyridine; potassium carbonate; In methanol;

DOI:10.1021/jo0100190

Reference yield:

Acetic acid (R)-1-(2-acetoxy-ethyl)-3-[((E)-hexa-3,5-dienyl)oxycarbonylamino]-propyl ester (743457-76-3) → {(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / methanol / 3 h / 20 °C

2: 1.57 g / pyridine / 20 °C

3: 86 percent / DCI / CH₂Cl₂ / 1 h

With pyridine; dichloroisoproterenol; potassium carbonate; In methanol; dichloromethane;

DOI:10.1021/jo0100190

upstream raw materials:

(E)-hexa-3,5-dien-1-ol

Downstream raw materials:

{(R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-pentyl}-carbamic acid (E)-hexa-3,5-dienyl ester