C₂₈H₂₄FNO₆S

Base Information

• Chemical Name: C₂₈H₂₄FNO₆S
• CAS No.: 1472655-22-3
• Molecular Formula: C₂₈H₂₄FNO₆S
• Molecular Weight: 521.566
• Mol file: 1472655-22-3.mol

Synonyms:C₂₈H₂₄FNO₆S

Chemical Property of C₂₈H₂₄FNO₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₄FNO₆S

There total 3 articles about C₂₈H₂₄FNO₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C28H25NO6S (1472655-18-7) → C28H24FNO6S (1472655-22-3)

Guidance literature:

C₂₈H₂₅NO₆S; With 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate; In methanol; acetonitrile; for 3h; Reflux;

With trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/ja408814g

Reference yield:

6H-Thieno[2,3-c]pyridin-7-one (28981-13-7) → C28H24FNO6S (1472655-22-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 0.67 h / 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate / methanol; acetonitrile / 3 h / Reflux

2.2: 1 h / 20 °C

With N,O-bis-(trimethylsilyl)-acetamide; 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/ja408814g

Reference yield:

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride (4330-21-6) → C28H24FNO6S (1472655-22-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 0.67 h / 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate / methanol; acetonitrile / 3 h / Reflux

2.2: 1 h / 20 °C

With N,O-bis-(trimethylsilyl)-acetamide; 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate; In methanol; dichloromethane; acetonitrile;

DOI:10.1021/ja408814g

upstream raw materials:

6H-Thieno[2,3-c]pyridin-7-one

2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

C₂₈H₂₅NO₆S

Downstream raw materials:

C₂₈H₂₄FNO₅S₂