C₁₆H₁₆F₃NO₃

Base Information

Chemical Name:C₁₆H₁₆F₃NO₃
CAS No.:1279093-59-2
Molecular Formula:C₁₆H₁₆F₃NO₃
Molecular Weight:327.303
Hs Code.:

C<sub>16</sub>H<sub>16</sub>F<sub>3</sub>NO<sub>3</sub>

Synonyms:C₁₆H₁₆F₃NO₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₁₆F₃NO₃

Chemical Property:

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Technology Process of C₁₆H₁₆F₃NO₃

There total 5 articles about C₁₆H₁₆F₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1279093-58-1
C₁₄H₁₇NO₂

: 407-25-0
trifluoroacetic anhydride

: 1279093-59-2
C₁₆H₁₆F₃NO₃

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 32365-96-1,68702-74-9,86462-82-0
methyl 3-(R)-methyl-5-hydroxypentanoate

: 1279093-59-2
C₁₆H₁₆F₃NO₃

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine; dimethyl sulfoxide; sulfur trioxide pyridine complex / dichloromethane / 2 h / 0 °C

2: potassium carbonate / methanol / 0 - 20 °C

3: diethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 0 - 20 °C

4: triethylamine / dichloromethane / 0 - 20 °C

With sulfur trioxide pyridine complex; potassium carbonate; dimethyl sulfoxide; diethylamine; triethylamine; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 63473-60-9
(R)-3-methylpentanedioic acid monomethyl ester

: 1279093-59-2
C₁₆H₁₆F₃NO₃

Guidance literature:: Multi-step reaction with 5 steps

1: dimethylsulfide borane complex / tetrahydrofuran / -15 - 20 °C

2: N-ethyl-N,N-diisopropylamine; dimethyl sulfoxide; sulfur trioxide pyridine complex / dichloromethane / 2 h / 0 °C

3: potassium carbonate / methanol / 0 - 20 °C

4: diethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 0 - 20 °C

5: triethylamine / dichloromethane / 0 - 20 °C

With dimethylsulfide borane complex; sulfur trioxide pyridine complex; potassium carbonate; dimethyl sulfoxide; diethylamine; triethylamine; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;