63473-60-9

Basic information

• Product Name: (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE
• Synonyms: (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE;(R)-MONO-METHYL 3-METHYLGLUTARATE;METHYL (R)-(+)-3-METHYLGLUTARATE;(r)-methyl mono-(3-methylglutarate);(R)-mono-Methyl 3-methylglutarate, (R)-Monomethyl 3-methylglutarate;(R)-Methyl mono-(3-methylglutarate), (R)-mono-Methyl 3-methylglutarate;(R)-3-Methylglutaric acid monomethyl ester;(R)-3-Methylpentanedioic acid monomethyl ester
• CAS NO: 63473-60-9
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 160.17
• Mol File: 63473-60-9.mol
• Article Data: 51

Chemical Properties

• Boiling Point: 103-104 °C0.4 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.125 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000479mmHg at 25°C
• Refractive Index: n20/D 1.438
• Storage Temp.: 2-8°C
• BRN: 1723141
• CAS DataBase Reference: (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE(63473-60-9)
• EPA Substance Registry System: (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE(63473-60-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 63473-60-9(Hazardous Substances Data)

Usage

General Description

(R)-1-Methyl Hydrogen 3-Methylglutarate is a chemical compound with the molecular formula C6H10O4. It is the (R)-enantiomer of 1-methyl hydrogen 3-methylglutarate and is commonly used in organic synthesis and chemical research. (R)-1-METHYL HYDROGEN 3-METHYLGLUTARATE is a derivative of glutaric acid and is known for its potential to be used in the production of pharmaceuticals and other industrial chemicals. It is also used as a chiral building block in the synthesis of various bioactive molecules. Additionally, (R)-1-Methyl Hydrogen 3-Methylglutarate has shown potential as a scaffold for the development of new drugs and bioactive compounds.

InChI:InChI=1/C7H12O4/c1-5(3-6(8)9)4-7(10)11-2/h5H,3-4H2,1-2H3,(H,8,9)/t5-/m1/s1

Upstream product

• 27151-65-1 3-methyl-1,5-pentanedioic acid monomethyl ester 
• 67-56-1 methanol 
• 108-55-4 glutaric anhydride, 
• 4166-53-4 3-methylglutaric anhydride 
• 19013-37-7 dimethyl 3-methylglutarate 
• 108330-16-1 (S)-3-Methyl-pentanedioic acid tert-butyl ester methyl ester 
• 65844-74-8 2-methylpropan-1,1,3-tricarboxylic acid trimethyl ester 
• 1753-40-8 (R)-4-menthen-3-one 
• 128217-53-8 (E,Z)-methyl 5-(benzyloxy)-2-pentenoate 
• 68702-74-9 (S)-methyl5-hydroxy-3-methylpentanoate 
• 626-51-7 3-methyl glutaric acid 
• 52313-87-8 3-methyl-2-pentene-1,5-diacid dimethyl 
• 108330-09-2 (+)-3-phenylselenomethyl glutaric acid methyl t-butyl mixed diester 
• 43080-04-2 3-(S)-methylpentanedioic acid mono-tert-butyl ester 

Downstream Products

• 65781-38-6 D-3-methyl-undecanoic acid 
• 13490-36-3 D-3-methyl-dodecanoic acid 
• 101577-55-3 (R)-3-methyl-octanedioic acid-8-benzyl ester-1-methyl ester 
• 13490-36-3 L-3-methyl-dodecanoic acid 
• 36237-75-9 (S,S)-3,6-Dimethyloctandisaeure-dimethylester 
• 34061-58-0 1,34-Tetratriacontandiol 
• 83483-71-0 (S)-21-Hydroxy-3-methylheneicosansaeure-methylester 
• 27151-65-1 3-methyl-1,5-pentanedioic acid monomethyl ester 
• 61898-55-3 (4R)-4-methyltetrahydro-2H-pyran-2-one 
• 68702-74-9 methyl 3-(R)-methyl-5-hydroxypentanoate 
• 61898-56-4 (S)-4-methyltetrahydro-2H-pyran-2-one 
• 936259-13-1 C₂₁H₃₁NO₅ 
• 936259-14-2 C₂₁H₂₇NO₅ 
• 912293-10-8 C₂₀H₃₆O₄SSi 

Relevant articles and documents

ENZYMES IN ORGANIC SYNTHESIS. 42. INVESTIGATION OF THE EFFECTS OF THE ISOZYMAL COMPOSITION OF PIG LIVER ESTERASE ON ITS STEREOSELECTIVITY IN PREPARATIVE-SCALE ESTER HYDROLYSES OF ASYMMETRIC SYNTHETIC VALUE.

The stereospecificities of the isozyme components of commercially available pig liver esterase have been shown to be essentially the same toward representative monocyclic and acyclic diester substrates. This removes previous concerns that the isozymal com

Cinchona alkaloid derivative modified Fe3O4nanoparticles for enantioselective ring opening of: Meso -cyclic anhydrides

In the present work, the molecular framework of quinidine was modified at the methoxy functional group of the C6′ carbon of the quinoline moiety with a long-chain carboxylic acid group (-COOH) and it was used as a capping agent during the synthesis of Fe3

Atropselective Synthesis of N,C-Bis(diphenylphosphanes) from Bridged 2-Arylindoles Based on Effective Point-to-Axial Asymmetric Inductions after an Unusual Dilithiation ⊥

An asymmetric methanolysis of glutaric anhydride and 6 ensuing steps gave veratrol-annulated dimethylcyclo-heptenone diastereomers with 99% ee; ring closures occurred by Friedel-Crafts acylations of carboxylic acids obtained by stereospecific hydrogenolyses of a pair of diastereomeric δ-lactones. The mentioned cycloheptenones and Ph-NH-NH2 underwent Fischer indole syntheses providing the tetracyclic indoles cis- and trans-14a, respectively. Double lithiations with BuLi and quenchings with ClPPh2 furnished the diphosphanes cis- and trans-15 with perfect (P)- and (M)-atropselectivity, respectively.

Enantioselective acyl-transfer catalysis by fluoride ions

The asymmetric nucleophilic catalysis by fluoride ions at a carbon-based electrophile has been demonstrated for the first time. Using a library of ad hoc designed bifunctional phase-transfer catalysts in which both the anion and the cation are directly involved in the reaction, the desymmetrisation of meso-succinic and -glutaric anhydrides is possible.19F NMR spectroscopic studies support the intermediacy of an acyl fluoride intermediate.