Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol

Base Information

• Chemical Name: Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol
• CAS No.: 1226758-58-2
• Molecular Formula: C₇₁H₁₀₆N₁₀O₁₃
• Molecular Weight: 1307.68

Synonyms:Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol

Chemical Property of Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol

There total 1 articles about Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

Nα,N',Nα,N'-tetrakis(3-aminopropyl)-L-β,γ-diaminopropanol hydrochloride + Boc-Phe-OTcp (7535-57-1) → Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol (1226758-58-2)

Guidance literature:

Nα,N',Nα,N'-tetrakis(3-aminopropyl)-L-β,γ-diaminopropanol hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 40 ℃;

Boc-Phe-OTcp; In N,N-dimethyl-formamide; at 20 ℃; for 168h;

DOI:10.3390/molecules14103881

Reference yield:

Boc-Lys(2-chlorocarbobenzoxy)-OH (195869-14-8) + Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol (1226758-58-2) → C127H174Cl4N18O25

Guidance literature:

Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

Boc-Lys(2-chlorocarbobenzoxy)-OH; With 1-hydroxy-pyrrolidine-2,5-dione; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.3390/molecules14103881

upstream raw materials:

Boc-Phe-OTcp

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