[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Base Information

Chemical Name:[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester
CAS No.:212514-37-9
Molecular Formula:C₁₄H₁₉NO₅S
Molecular Weight:313.375
Hs Code.:

Synonyms:[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Suppliers and Price of [(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of [(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

There total 4 articles about [(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59943-97-4,28819-01-4
(S)-methyl 2-((ethoxycarbonyl)amino)propanoate

: α-lithio methyl tolyl sulfone

: 212514-37-9
[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Guidance literature:: In tetrahydrofuran; at -78 ℃;
DOI:10.1016/S0040-4020(98)00533-X

Reference yield:

: 128913-43-9
N-ethoxycarbonyl-L-alanyl diazomethane

: 212514-37-9
[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 47percent HBr / diethyl ether / 0.75 h / 0 °C

2: dimethylformamide / 0.5 h / Ambient temperature

With hydrogen bromide; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1080/00397919808004476

Reference yield:

: 128913-43-9
N-ethoxycarbonyl-L-alanyl diazomethane

: 824-79-3
sodium 4-methylbenzenesulfinate

: 212514-37-9
[(S)-1-Methyl-2-oxo-3-(toluene-4-sulfonyl)-propyl]-carbamic acid ethyl ester

Guidance literature:: With hydrogen bromide; Multistep reaction; 1.) Et₂O, 0 deg C, 2.) DMF, room temperature;
DOI:10.1016/S0040-4020(98)00533-X