(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline
CAS No.:1016275-44-7
Molecular Formula:C₁₅H₁₄FN
Molecular Weight:227.281
Hs Code.:

Synonyms:(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

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Chemical Property of (S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

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Technology Process of (S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

There total 16 articles about (S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1159987-21-9
2-(3-(4-fluorophenyl)prop-2-ynyl)aniline

: 1016275-44-7
(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With methyl(triphenylphosphine)gold(I); (R)‐3,3′‐bis(9‐phenanthryl)‐1,1′‐binaphthalene‐2,2′‐diyl hydrogen phosphate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In toluene; at 25 ℃; for 16h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja903547q

Reference yield: 98.0%

: 323-91-1
2-(4-fluoro-phenyl)-quinoline

: 1016275-44-7
(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; C₄₆H₃₈F₆FeN₂P₂S; hydrogen; acetic acid; In ethanol; at 20 ℃; for 12h; under 38002.6 Torr; enantioselective reaction;
DOI:10.1021/acscatal.1c01353

Reference yield: 90.0%

: C₁₅H₁₂FNO

: 1016275-44-7
(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline(S)-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (R)-3,3'-bis(9-phenylanthracen-10-yl)-1,1'-binapthyl-2,2'-diyl-phosphoric acid; In ethyl acetate; at 20 ℃; for 18h; enantioselective reaction; Irradiation;
DOI:10.1021/acs.orglett.9b01354