prasugrel monohydrogensulfate

Base Information

• Chemical Name: prasugrel monohydrogensulfate
• CAS No.: 1191933-01-3
• Molecular Formula: C₂₀H₂₀FNO₃S*H₂O₄S
• Molecular Weight: 471.528
• Mol file: 1191933-01-3.mol

Synonyms:prasugrel monohydrogensulfate

Chemical Property of prasugrel monohydrogensulfate

Chemical Property:

Purity/Quality:

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Technology Process of prasugrel monohydrogensulfate

There total 2 articles about prasugrel monohydrogensulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

prasugel (150322-43-3) → prasugrel monohydrogensulfate (1191933-01-3)

Guidance literature:

With sulfuric acid; In acetone; at -5 ℃; for 1.25h;

Reference yield: 50.0%

2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine maleate → prasugrel monohydrogensulfate (1191933-01-3)

Guidance literature:

With sulfuric acid; In acetone; at 0 - 60 ℃;

upstream raw materials:

prasugel

Refernces

• 1、 -. "Prasugrel hydrogen sulfate crystal form IV and preparation method thereof". Paragraph 0030; 0033; 0036; 0038; 0039; 0042; 0045. . Retrieved 2018/04/28.
• 2、 -. "THE HYDROSULFATE OF PRASUGREL, ITS PHARMACEUTICAL COMBINATION AND USES THEREOF". Page/Page column 7-8. . Retrieved 2011/06/23.