OCTADECANEDIOIC ACID MONOBENZYL ESTER

Base Information

• Chemical Name: OCTADECANEDIOIC ACID MONOBENZYL ESTER
• CAS No.: 189625-51-2
• Molecular Formula: C₂₅H₄₀O₄
• Molecular Weight: 404.59
• Hs Code.: 2918990090
• Mol file: 189625-51-2.mol

Synonyms:Octadecanedioicacid, mono(phenylmethyl) ester (9CI)

Chemical Property of OCTADECANEDIOIC ACID MONOBENZYL ESTER

Chemical Property:

• Boiling Point: 529.1±23.0 °C(Predicted)
• PKA: 4.78±0.10(Predicted)
• PSA: 63.60000
• Density: 1.008±0.06 g/cm3(Predicted)
• LogP: 7.05600

Purity/Quality:

98% ^*data from raw suppliers

18-(Benzyloxy)-18-oxooctadecanoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of OCTADECANEDIOIC ACID MONOBENZYL ESTER

There total 5 articles about OCTADECANEDIOIC ACID MONOBENZYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

octadecanedioic acid (871-70-5) + benzyl alcohol (100-51-6,185532-71-2) → 18-(benzyloxy)-18-oxooctadecanoic acid (189625-51-2)

Guidance literature:

With sulfuric acid; In toluene; Reagent/catalyst; Reflux;

Reference yield: 58.2%

octadecanedioic acid (871-70-5) + benzyl bromide (100-39-0) → 18-(benzyloxy)-18-oxooctadecanoic acid (189625-51-2)

Guidance literature:

With potassium hydrogencarbonate; In 2-methyltetrahydrofuran; water; at 75 ℃; for 30h;

Reference yield: 28.0%

octadecanedioic acid (871-70-5) + benzyl alcohol (100-51-6,185532-71-2) → 18-(benzyloxy)-18-oxooctadecanoic acid (189625-51-2) + dibenzyl octadecanedioate

Guidance literature:

octadecanedioic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 0 ℃;

benzyl alcohol; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

upstream raw materials:

octadecanedioic acid

benzyl alcohol

benzyl bromide

Refernces

• 1、 -. "Method for preparing long aliphatic chain diacid derivative and application of long aliphatic chain diacid derivative". Paragraph 0172-0175. . Retrieved 2021/07/01.
• 2、 -. "METHODS OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GROWTH DIFFERENTIATION FACTOR 15 (GDF-15)". Paragraph 00289 - 00291. . Retrieved 2017/08/01.