2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

Base Information

Chemical Name:2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide
CAS No.:1040741-70-5
Molecular Formula:C₂₅H₃₅IN₄O₂
Molecular Weight:550.483
Hs Code.:

Synonyms:2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

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Chemical Property of 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

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Technology Process of 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

There total 1 articles about 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 69696-38-4
5-iodo-2-isopropyl-6-methyl-pyrimidin-4-ol

: 1197-58-6
1-(isocyanomethyl)-4-methoxybenzene

: 107-11-9,30551-89-4
1-amino-2-propene

: 590-86-3
isovaleraldehyde

: 1040741-70-5
2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

Guidance literature:: In methanol; at 60 ℃; for 72h; Inert atmosphere;
DOI:10.1021/ol801217a

Reference yield: 80.0%

: 1040741-70-5
2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

: 1040741-78-3
2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-methoxy-benzylamide

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In methanol; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol801217a

Reference yield:

: 1040741-70-5
2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxy-benzylamide

: 1040741-79-4
2-(2-isopropyl-4-methyl-6-methylene-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-methoxy-benzylamide

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In methanol; at 80 ℃; Inert atmosphere;
DOI:10.1021/ol801217a