2-bromocyclopentanone

Base Information

• Chemical Name: 2-bromocyclopentanone
• CAS No.: 1056246-36-6
• Molecular Formula: C₅H₇BrO
• Molecular Weight: 163.014
• Mol file: 1056246-36-6.mol

Synonyms:2-bromocyclopentanone

Chemical Property of 2-bromocyclopentanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromocyclopentanone

There total 4 articles about 2-bromocyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.6%

cyclopentanone (120-92-3) → 2-cyclopentylidenecyclopentan-1-one (825-25-2) + 2-bromocyclopentanone (1056246-36-6)

Guidance literature:

With n-Butyl chloride; bromine; at 1 ℃; for 12h;

Reference yield:

cyclopentanone hydroperoxide (18622-31-6) → 5-bromopentanoic acid (2067-33-6) + α,α'-dibromocyclopentanone + 2-bromocyclopentanone (1056246-36-6)

Guidance literature:

With hydrogen bromide; sodium bromide; copper(ll) bromide; In water; at 25 ℃;

DOI:10.1007/BF00953707

Reference yield:

2-Bromocyclopentanone 1,2-ethanediyl acetal (82235-82-3) → 2-chlorocyclopentanone (694-28-0) + 2-bromocyclopentanone (1056246-36-6)

Guidance literature:

With silica gel; iron(III) chloride; at 20 ℃; for 0.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1055/s-1987-27833

upstream raw materials:

cyclopentanone hydroperoxide

2-Bromocyclopentanone 1,2-ethanediyl acetal

Cyclopentanol

cyclopentanone

Downstream raw materials:

2-benzylidenecyclopentanone

2-Buthylidenecyclopentenone

cyclopentane-1,2-dione dioxime

(2-oxo-cyclopentyl)-triphenyl-phosphonium; bromide

Refernces

• 1、 -. "Process for producing 2-bromocyclopentanone". Page column 4. . Retrieved 2008/06/13.
• 2、 Fadel, Antoine,Yefsah, Ramdane,Salauen, Jacques. "Anhydrous Iron(III) Chloride Dispersed on Silica Gel; III. A Convenient and Mild Reagent for Deacetalization in Dry Medium". . p. 37 - 40. Retrieved 2007/10/02.