N-(2,3-Dihydroxybenzoyl)-D-serine

Base Information

Chemical Name:N-(2,3-Dihydroxybenzoyl)-D-serine
CAS No.:21948-12-9
Molecular Formula:C₁₀H₁₁NO₆
Molecular Weight:241.2
Hs Code.:
DSSTox Substance ID:DTXSID201300574
Nikkaji Number:J2.587.191J

Synonyms:N-(2,3-Dihydroxybenzoyl)-D-serine;SCHEMBL11247265;DTXSID201300574;21948-12-9

Suppliers and Price of N-(2,3-Dihydroxybenzoyl)-D-serine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,3-Dihydroxybenzoyl)-D-serine

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:241.05863707
Heavy Atom Count:17
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)O)O)C(=O)NC(CO)C(=O)O
Isomeric SMILES:C1=CC(=C(C(=C1)O)O)C(=O)N[C@H](CO)C(=O)O

Technology Process of N-(2,3-Dihydroxybenzoyl)-D-serine

There total 7 articles about N-(2,3-Dihydroxybenzoyl)-D-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1027343-23-2
2,3-dibenzyloxybenzoyl-D-serine

: 21948-12-9,127658-43-9
2,3-dihydroxybenzoyl-D-serine

Guidance literature:: With 5% Pd/C; hydrogen; In methanol; at 20 ℃; for 3h;
DOI:10.1039/b719713f

Reference yield: 93.0%

: 78088-92-3
(S)-3-Benzyloxy-2-(2,3-bis-benzyloxy-benzoylamino)-propionic acid

: 21948-09-4,127658-43-9
2,3-Dihydroxy-N-benzoyl-serin

: 21948-12-9,127658-43-9
2,3-dihydroxybenzoyl-D-serine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; acetic acid; Title compound not separated from byproducts;
DOI:10.1021/jo00331a001

Reference yield:

: 5779-91-9
2,3-bis(benzyloxy)benzaldehyde

: 21948-12-9,127658-43-9
2,3-dihydroxybenzoyl-D-serine

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / H₂NSO₃H, NaClO₂ / acetone; H₂O / 1 h / Ambient temperature

2: 94 percent / oxalyl chloride / DMF / benzene / 0.5 h / 5 °C

3: 78 percent / NaOH / H₂O; tetrahydrofuran / 1.) 1h, 0 deg C, 2.) 2h, r.t.

4: H₂ / Pd/C(10percent) / ethanol; acetic acid

With sodium hydroxide; sodium chlorite; oxalyl dichloride; aminosulfonic acid; hydrogen; palladium on activated charcoal; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol; water; acetic acid; acetone; benzene;
DOI:10.1021/jo00331a001