Dibenzyloxybenzaldehyde

Base Information

• Chemical Name: Dibenzyloxybenzaldehyde
• CAS No.: 5779-91-9
• Molecular Formula: C21H18O3
• Molecular Weight: 318.372
• DSSTox Substance ID: DTXSID40446605
• Nikkaji Number: J1.383.173D
• Wikidata: Q82265317
• Mol file: 5779-91-9.mol

Synonyms:dibenzyloxybenzaldehyde;2,3-dibenzyloxybenzaldehyde;5779-91-9;2,3-Di(benzyloxy)benzaldehyde;2,3-bis-benzyloxy-benzaldehyde;SCHEMBL1050281;2,3-Bis(benzyloxy)benzaldehyde;DTXSID40446605;RBNBFXRIYVDZBU-UHFFFAOYSA-N

Chemical Property of Dibenzyloxybenzaldehyde

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 318.125594432
• Heavy Atom Count: 24
• Complexity: 358

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=CC(=C2OCC3=CC=CC=C3)C=O

Technology Process of Dibenzyloxybenzaldehyde

There total 5 articles about Dibenzyloxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dihydroxybenzaldehyde (24677-78-9) + benzyl chloride (100-44-7) → 2,3-bis(benzyloxy)benzaldehyde (5779-91-9)

Guidance literature:

With iodine; potassium carbonate; In ethanol; at 5 ℃; for 5h; Reflux;

Reference yield: 93.0%

2,3-dihydroxybenzaldehyde (24677-78-9) + benzyl bromide (100-39-0) → 2,3-bis(benzyloxy)benzaldehyde (5779-91-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1002/chem.202003805

Reference yield: 65.0%

2,3-dihydroxybenzaldehyde (24677-78-9) + benzyl chloride (100-44-7) → 2,3-bis(benzyloxy)benzaldehyde (5779-91-9) + 3-benzyloxy-2-hydroxybenzaldehyde (86734-59-0)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; at 25 ℃; for 17h; Yields of byproduct given; NaH : pyrocatechlol 2.2;

DOI:10.1039/c39830000400

upstream raw materials:

2,3-dihydroxybenzaldehyde

benzyl chloride

benzyl bromide

benzaldehyde

Downstream raw materials:

(E)-2,3-bis-benzyloxy-β-nitro-styrene

1-(2,3-bis-benzyloxy-phenyl)-pentadecan-1-ol

2,3-dibenzyloxybenzoic acid

2,3-bis-benzyloxy-benzyl alcohol