C₁₈H₂₂ClN₃O₃

Base Information

Chemical Name:C₁₈H₂₂ClN₃O₃
CAS No.:1187660-22-5
Molecular Formula:C₁₈H₂₂ClN₃O₃
Molecular Weight:363.844
Hs Code.:

C<sub>18</sub>H<sub>22</sub>ClN<sub>3</sub>O<sub>3</sub>

Synonyms:C₁₈H₂₂ClN₃O₃

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Chemical Property of C₁₈H₂₂ClN₃O₃

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Technology Process of C₁₈H₂₂ClN₃O₃

There total 1 articles about C₁₈H₂₂ClN₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 58885-58-8
N-tert-butoxycarbonyl-3-aminopropanol

: 2-chloro-4-(p-hydroxyphenyl)pyrimidine

: 1187660-22-5
C₁₈H₂₂ClN₃O₃

Guidance literature:: With diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 3h;

Reference yield: 35.0%

: 759456-60-5
(5-amino-2-morpholinophenyl)methanol

: 1187660-22-5
C₁₈H₂₂ClN₃O₃

: 1187660-23-6
C₂₉H₃₇N₅O₅

Guidance literature:: With potassium carbonate; XPhos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tert-butyl alcohol; at 80 ℃; Inert atmosphere of N₂;

Reference yield:

: 1187660-22-5
C₁₈H₂₂ClN₃O₃

: 1187660-63-4
C₂₆H₃₃ClN₆O₃

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; XPhos / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / tert-butyl alcohol / 80 °C / Inert atmosphere of N₂

2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; XPhos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In N,N-dimethyl-formamide; tert-butyl alcohol; 1: Buchwald-Hartwig Pd catalyzed aryl C-N formation;