7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Base Information

Chemical Name:7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate
CAS No.:1361005-41-5
Molecular Formula:C₂₇H₂₁ClF₃NO₄
Molecular Weight:515.916
Hs Code.:

Synonyms:7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Suppliers and Price of 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

There total 8 articles about 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1361004-87-6
7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4(1H)-one

: 541-41-3
chloroformic acid ethyl ester

: 1361005-41-5
7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Guidance literature:: 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4(1H)-one; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

chloroformic acid ethyl ester; In tetrahydrofuran; for 0.5h; Inert atmosphere;
DOI:10.1021/jm201179h

Reference yield: 67.0%

: 1361005-41-5
7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Guidance literature:

Reference yield:

: 1361005-59-5
4-(4-(trifluoromethoxy)benzyl)benzaldehyde

: 1361005-41-5
7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4-ylethyl carbonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: diethyl ether / 1 h / 0 °C / Inert atmosphere

2.1: pyridinium chlorochromate / dichloromethane / 20 °C / Inert atmosphere

3.1: toluene-4-sulfonic acid / butan-1-ol / 24 h / 130 °C / Inert atmosphere

4.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

4.2: 0.5 h / Inert atmosphere

With potassium tert-butylate; toluene-4-sulfonic acid; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane; butan-1-ol; 1.1: Grignard reaction;
DOI:10.1021/jm201179h