(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

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Chemical Name:(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene
CAS No.:314297-17-1
Molecular Formula:C₃₂H₃₉NO₆SSi
Molecular Weight:593.816
Hs Code.:

(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

Synonyms:(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

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Chemical Property of (2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

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Technology Process of (2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

There total 2 articles about (2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 314297-16-0
Toluene-4-sulfonic acid (3aR,5S,6S,6aR)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-6-(toluene-4-sulfonylamino)-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester

: 314297-17-1
(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0040-4039(03)01279-6

Reference yield:

: 247025-11-2
3'-azido-5'-O-tert-butyldiphenylsilyl-3'-deoxy-4'-hydroxymethyl-1',2'-O-isopropylidene-α-D-ribofuranose

: 314297-17-1
(2aS,2bR,5aR,6aS)-6a-(tert-Butyl-diphenyl-silanyloxymethyl)-4,4-dimethyl-2-(toluene-4-sulfonyl)-hexahydro-3,5,6-trioxa-2-aza-cyclobuta[a]pentalene

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd-C / ethyl acetate / 20 °C

2: DMAP; Et₃N / CH₂Cl₂ / 20 °C

3: 90 percent / NaH / tetrahydrofuran / 20 °C

With dmap; hydrogen; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1016/S0040-4039(03)01279-6