2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Base Information

Chemical Name:2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide
CAS No.:1257521-27-9
Molecular Formula:C₁₃H₁₂F₇NO
Molecular Weight:331.233
Hs Code.:

Synonyms:2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Suppliers and Price of 2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

There total 2 articles about 2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5856-77-9
2,2-dimethylbutanoyl chloride

: 651-83-2
4-trifluoromethyl-2,3,5,6-tetrafluoroaniline

: 1257521-27-9
2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Guidance literature:: In toluene; for 12h; Reflux;
DOI:10.1021/ja108754f

Reference yield:

: 595-37-9
2,2-dimethylbutyric acid

: 1257521-27-9
2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 0 - 20 °C / Inert atmosphere

2: toluene / 12.5 h / 20 °C / Reflux; Schlenk technique

With oxalyl dichloride; In dichloromethane; toluene;
DOI:10.1002/anie.201502075

Reference yield: 99.0%

: 201230-82-2
carbon monoxide

: 1257521-27-9
2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)butanamide

: 1257521-47-3
3-ethyl-3-methyl-1-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pyrrolidine-2,5-dione

Guidance literature:: With potassium dihydrogenphosphate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; silver(I) acetate; palladium diacetate; In hexane; at 130 ℃; for 18h; under 760.051 Torr;
DOI:10.1021/ja108754f