Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)-

Base Information

Chemical Name:Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)-
CAS No.:188818-73-7
Molecular Formula:C₁₁H₂₁NO₂
Molecular Weight:199.293
Hs Code.:
Mol file:188818-73-7.mol

Synonyms:Cyclohexanecarboxylicacid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)- (9CI)

Suppliers and Price of Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)-

Chemical Property:

PSA：52.32000
LogP:2.54590

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)-

There total 4 articles about Cyclohexanecarboxylic acid, 2-amino-, 1,1-dimethylethyl ester, (1S-trans)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 151294-67-6
(1S,2R)-2-[Benzyl-((R)-1-phenyl-ethyl)-amino]-cyclohexanecarboxylic acid tert-butyl ester

: 188818-73-7,739351-45-2
t-Butyl (+/-)-cis-2-aminocyclohexanecarboxylate

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; for 16h; under 4560 Torr; Yield given; Ambient temperature;
DOI:10.1039/a804660c

Reference yield:

: 22173-21-3
tert-butyl cyclohex-1-ene-1-carboxylate

: 188818-73-7,739351-45-2
t-Butyl (+/-)-cis-2-aminocyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / BuLi / tetrahydrofuran / 1.) -78 deg C to 0 deg C, 10 min, 2.) -78 deg C, 21 h

2: H₂ / Pd(OH)2 / methanol / 16 h / 4560 Torr / Ambient temperature

With n-butyllithium; hydrogen; palladium dihydroxide; In tetrahydrofuran; methanol;
DOI:10.1039/a804660c