alpha,3-Dimethylbenzeneacetyl chloride

Base Information

Chemical Name:alpha,3-Dimethylbenzeneacetyl chloride
CAS No.:928850-14-0
Molecular Formula:C₁₀H₁₁ClO
Molecular Weight:182.65
Hs Code.:
DSSTox Substance ID:DTXSID701298273

Synonyms:SCHEMBL2153144;DTXSID701298273;alpha,3-Dimethylbenzeneacetyl chloride;928850-14-0

Suppliers and Price of alpha,3-Dimethylbenzeneacetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of alpha,3-Dimethylbenzeneacetyl chloride

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:182.0498427
Heavy Atom Count:12
Complexity:167

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C(C)C(=O)Cl

Technology Process of alpha,3-Dimethylbenzeneacetyl chloride

There total 2 articles about alpha,3-Dimethylbenzeneacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73721-06-9,213406-28-1,601472-22-4
2-(3-methylphenyl)propanoic acid

: 928850-14-0
2-(m-tolyl)propanoyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 1h;

Reference yield:

: 621-36-3
m-methylphenylacetic acid

: 928850-14-0
2-(m-tolyl)propanoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2.33 h / 0 °C / Inert atmosphere

1.2: 0 - 22 °C / Inert atmosphere

2.1: thionyl chloride / dichloromethane / 15 h / 20 °C / Inert atmosphere

With n-butyllithium; thionyl chloride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja300799t