2-(m-Tolyl)propanoic acid

Base Information

Chemical Name:2-(m-Tolyl)propanoic acid
CAS No.:73721-06-9
Molecular Formula:C₁₀H₁₂O₂
Molecular Weight:164.204
Hs Code.:
European Community (EC) Number:887-846-1
Nikkaji Number:J967.193E

Synonyms:2-(3-methylphenyl)propanoic acid

Suppliers and Price of 2-(m-Tolyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 2-(m-Tolyl)propanoic acid

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:164.083729621
Heavy Atom Count:12
Complexity:165

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C(C)C(=O)O

Technology Process of 2-(m-Tolyl)propanoic acid

There total 15 articles about 2-(m-Tolyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 621-36-3
m-methylphenylacetic acid

: 74-88-4
methyl iodide

: 73721-06-9,213406-28-1,601472-22-4
2-(3-methylphenyl)propanoic acid

Guidance literature:: m-methylphenylacetic acid; With lithium diisopropyl amide; In tetrahydrofuran; at -20 - -10 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at -20 - 0 ℃; for 0.5h; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield: 93.0%

: 100-80-1
3-methylstyrene

: 124-38-9,18923-20-1
carbon dioxide

: 73721-06-9,213406-28-1,601472-22-4
2-(3-methylphenyl)propanoic acid

Guidance literature:: 3-methylstyrene; With N-(2,6-diisopropylphenyl)-N-((1E)-1-(6-[(1E)-N-(2,6-diisopropylphenyl)ethanimidoyl]pyridin-2-yl)ethylidene)amine; ethylmagnesium bromide; iron(II) chloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 2h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; diethyl ether; for 0.5h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ja3045053

Reference yield: 91.0%

: 100-80-1
3-methylstyrene

: 201230-82-2
carbon monoxide

: 73721-06-9,213406-28-1,601472-22-4
2-(3-methylphenyl)propanoic acid

Guidance literature:: With iron(III) chloride; water; palladium diacetate; triphenylphosphine; In 1,4-dioxane; at 80 ℃; for 10h; under 37503.8 Torr; regioselective reaction; Sealed tube; Inert atmosphere; Autoclave;
DOI:10.1039/c8cc01190g