Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate

Base Information

Chemical Name:Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate
CAS No.:188656-16-8
Molecular Formula:C7H10BrNO3
Molecular Weight:236.06
Hs Code.:
Nikkaji Number:J820.513B
Mol file:188656-16-8.mol

Synonyms:188656-16-8;METHYL-(2Z)-2-ACETYLAMINO-3-BROMO-2-BUTENOATE;2-Butenoic acid, 2-(acetylamino)-3-bromo-, methyl ester, (2Z)-;A1-04778

Suppliers and Price of Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-(2Z)-2-ACETYLAMINO-3-BROMO-2-BUTENOATE 98.00%
5MG
$ 501.47

A1 Biochem Labs
Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate 95%
5 g
$ 1250.00

Total 2 raw suppliers

Chemical Property of Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.504
Boiling Point:352.948°C at 760 mmHg
Flash Point:167.257°C
PSA：55.40000
Density:1.476g/cm³
LogP:1.31280
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:234.98441
Heavy Atom Count:12
Complexity:235

Purity/Quality:

95% ^*data from raw suppliers

METHYL-(2Z)-2-ACETYLAMINO-3-BROMO-2-BUTENOATE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=C(C(=O)OC)NC(=O)C)Br
Isomeric SMILES:C/C(=C(\C(=O)OC)/NC(=O)C)/Br

Technology Process of Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate

There total 4 articles about Methyl-(2Z)-2-acetylamino-3-bromo-2-butenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 57294-56-1,60027-53-4,60027-59-0
(Z)-methyl 2-acetamido-3-methoxyacrylate

: 188656-15-7
(E)-methyl-2-acetamido-3-bromobut-2-enoate

: 188656-16-8
(Z)-2-Acetylamino-3-bromo-but-2-enoic acid methyl ester

Guidance literature:: With N-Bromosuccinimide; triethylamine; Yields of byproduct given;
DOI:10.1016/S0040-4039(98)00604-2

Reference yield:

: 3373-59-9
L-threonine methyl ester

: 188656-16-8
(Z)-2-Acetylamino-3-bromo-but-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaOAc

2.1: Et₃N / methanol

3.1: NBS / CH₂Cl₂

3.2: Et₃N / CH₂Cl₂

With N-Bromosuccinimide; sodium acetate; triethylamine; In methanol; dichloromethane;
DOI:10.1021/ja049499d

Reference yield:

: 2458-78-8
methyl (2S,3R)-2-(acetylamino)-3-hydroxybutanoate

: 188656-16-8
(Z)-2-Acetylamino-3-bromo-but-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: Et₃N / methanol

2.1: NBS / CH₂Cl₂

2.2: Et₃N / CH₂Cl₂

With N-Bromosuccinimide; triethylamine; In methanol; dichloromethane;
DOI:10.1021/ja049499d